Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.32 |
| ▸ | TUBB | P07437 | 4/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6315421 | 0.90 | MAPK1 (0.35) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL6316898 | 0.89 | ACHE (0.36) | ALDH1A1LMNAMAPTMAPK1KMT2A | |
| SCHEMBL6321863 | 0.86 | SLC9A1 (0.35) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL6314713 | 0.83 | MAPT (0.35) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL7120925 | 0.83 | TUBB1 (0.39) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL6315611 | 0.82 | TUBB1 (0.40) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL6317758 | 0.82 | TUBB4A (0.41) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL6317102 | 0.81 | TUBB4A (0.38) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL6316259 | 0.79 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL6316501 | 0.78 | PDK1 (0.35) | LMNAMAPTMAPK1TUBB1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887904-B2 | Substituted arylcycloalkanes, compositions containing them and use thereof | AVENTIS PHARMA S. A. (FR) | 2005-05-03 | — | — | US | disclosed |
| US-20030149072-A1 | Substituted arylcycloalkanes, compositions containing them and use thereof | AVENTIS PHARMA S.A. (FR) | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149072-A1 | Substituted arylcycloalkanes, compositions containing them and use thereof | ABL1, MCL1, AHR | ALDH1A1 682/4885LMNA 3280/4885MAPT 4538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.