Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.65 |
| ▸ | HTR1A | P08908 | 11/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635345 | 0.89 | HTR1A (0.60) | ADRB3HTR1AADRB2ADRB1CYP1A2 | |
| SCHEMBL6056296 | 0.81 | HTR1A (0.71) | ADRB3HTR1AADRB2ADRB1CYP1A2 | |
| SCHEMBL7769568 | 0.80 | HTR1A (0.48) | ADRB3HTR1AADRB2ADRB1CYP1A2 | |
| SCHEMBL7769566 | 0.80 | HTR1A (0.48) | ADRB3HTR1AADRB2ADRB1CYP1A2 | |
| SCHEMBL16549970 | 0.80 | ADRB2 (0.70) | ADRB3HTR1AADRB2ADRB1CYP1A2 | |
| SCHEMBL7641388 | 0.79 | HTR1A (0.61) | ADRB3HTR1AADRB2ADRB1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6539677 | 0.79 | ADRB3 (0.76) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7296138 | 0.78 | ADRB3 (0.78) | ADRB3ADRB2ADRB1 | |
| SCHEMBL4845543 | 0.78 | HTR1A (0.76) | ADRB3HTR1AADRB2ADRB1CYP1A2 | |
| SCHEMBL8698379 | 0.77 | HTR1A (1.00) | ADRB3HTR1AADRB2ADRB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043371-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20030181726-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043371-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB3, ADRB2 | ADRB3 2/4885HTR1A 633/4885ADRB2 3/4885 |
| US-20030181726-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB3, ADRB2 | ADRB3 2/4885HTR1A 422/4885ADRB2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.