SCHEMBL6322364

SCHEMBL6322364

Cc1ccc(S(=O)(=O)c2cc(N)ccc2O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.57
GAA P10253 8/20 0.50
ALDH1A1 P00352 4/20 0.50
PKM P14618 1/20 0.50
POLB P06746 3/20 0.49
MAPT P10636 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
USP2 O75604 1/20 0.48
HTT P42858 1/20 0.48
HKDC1 Q2TB90 1/20 0.48
GFER P55789 1/20 0.47
COMT P21964 1/20 0.47
KDM4E B2RXH2 2/20 0.47
RECQL P46063 1/20 0.47
CASP6 P55212 1/20 0.47
ELAVL1 Q15717 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17774545 0.90 HKDC1 (0.57) L3MBTL1GAAALDH1A1PKMPOLB
SCHEMBL6811093 0.87 GAA (0.48) L3MBTL1GAAALDH1A1POLBMAPT
SCHEMBL7774119 0.86 POLB (0.60) L3MBTL1GAAALDH1A1PKMPOLB
SCHEMBL9001313 0.86 L3MBTL1 (0.63) L3MBTL1GAAALDH1A1PKMPOLB
SCHEMBL656872 0.84 L3MBTL1 (0.61) L3MBTL1GAAALDH1A1PKMPOLB
SCHEMBL8527259 0.84 L3MBTL1 (0.61) L3MBTL1GAAALDH1A1PKMPOLB
SCHEMBL3653050 0.83 GAA (0.52) L3MBTL1GAAALDH1A1PKMPOLB
SCHEMBL17774551 0.83 POLB (0.69) L3MBTL1GAAALDH1A1POLBMAPT
SCHEMBL10489221 0.83 GAA (0.71) L3MBTL1GAAALDH1A1PKMPOLB
SCHEMBL9301172 0.82 ALDH1A1 (0.56) L3MBTL1GAAALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9872822-B2 Process for dyeing in the presence of oxidation bases comprising at least one sulfonic, sulfonamide, sulfone, amid or acid group and a metal catalyst, device and ready-to-use composition L'OREAL (FR) 2018-01-23 US disclosed
US-9872822-B2 Process for dyeing in the presence of oxidation bases comprising at least one sulfonic, sulfonamide, sulfone, amid or acid group and a metal catalyst, device and ready-to-use composition L'OREAL (FR) 2018-01-23 US disclosed
US-20160143826-A1 PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION L'OREAL (FR) 2016-05-26 US disclosed
US-20160143826-A1 PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION L'OREAL (FR) 2016-05-26 US disclosed
US-6875726-B2 Heat-sensitive recording material and process for production of the same OJI PAPER CO., LTD. (JP) 2005-04-05 US disclosed
EP-1231073-B1 Heat-sensitive recording material and process for production of the same OJI PAPER CO (JP) 2004-07-21 EP disclosed
US-20020155951-A1 Heat-sensitive recording material and process for production of the same OJI PAPER CO., LTD. (JP) 2002-10-24 US disclosed
EP-1231073-A1 Heat-sensitive recording material and process for production of the same Oji Paper Co., Ltd. (JP) 2002-08-14 EP disclosed
JP-2002160462-A HEAT-SENSITIVE RECORDING MEDIUM OJI PAPER CO LTD 2002-06-04 JP disclosed
JP-2002120460-A HEAT-SENSITIVE RECORDING BODY OJI PAPER CO LTD 2002-04-23 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160143826-A1 PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION KRT18, ARSA, SQOR L3MBTL1 4874/4885GAA 872/4885ALDH1A1 440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.