Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639306 | 0.93 | GAA (0.59) | POLBMAPK1FAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL20377184 | 0.91 | SMN1; SMN2 (0.64) | POLBMAPK1FAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL6322393 | 0.91 | SMN1; SMN2 (0.64) | POLBMAPK1FAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL29769770 | 0.90 | ALOX5 (0.65) | POLBMAPK1FAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL26374 | 0.88 | GAA (0.65) | MAPK1ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL16335594 | 0.86 | PKM (0.68) | POLBMAPK1FAAHALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7895043 | 0.86 | GAA (0.62) | MAPK1ALDH1A1SMN1; SMN2GAAMAPT | |
| Acetic Acid SCHEMBL28965272 | 0.84 | GAA (0.62) | POLBMAPK1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL26654348 | 0.84 | GAA (0.57) | MAPK1ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL9333093 | 0.84 | KMT2A (0.66) | POLBMAPK1ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158146-A1 | HSP70 Inhibitors and Methods of Using Same | THE WISTAR INST (US) | 2023-05-25 | — | — | US | disclosed |
| EP-2910561-A1 | Sialic acid derivatives | Brossmer, Reinhard (DE) | 2015-08-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158146-A1 | HSP70 Inhibitors and Methods of Using Same | HSPA2, HSPBP1, HSP90AB1 | POLB 2670/4885MAPK1 1140/4885FAAH 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.