SCHEMBL1401845

SCHEMBL1401845

C=CC(=O)NCCCCCCCCCCNC(=O)C=C

nearest known ligand 0.79

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ZDHHC20 Q5W0Z9 1/20 0.79
▸ ZDHHC2 Q9UIJ5 1/20 0.79
▸ ALDH1A1 P00352 3/20 0.59
▸ MAPK1 P28482 2/20 0.59
▸ TSHR P16473 1/20 0.59
▸ TDP1 Q9NUW8 1/20 0.59
▸ TGM2 P21980 4/20 0.53
▸ MAPT P10636 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.46
▸ HIF1A Q16665 1/20 0.46
▸ GAA P10253 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ EPHX1 P07099 4/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ ALDH1A2 O94788 1/20 0.41
▸ ALDH2 P05091 1/20 0.41
▸ ALDH1A3 P47895 1/20 0.41
▸ PRMT1 Q99873 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1591868 1.00 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL270209 1.00 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL269468 1.00 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL8405507 1.00 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL1592093 1.00 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL58169 1.00 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL632264 0.97 ZDHHC20 (0.75) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL1561467 0.92 ZDHHC20 (0.68) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL24652920 0.91 ZDHHC20 (0.68) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR
SCHEMBL10777565 0.91 ALDH1A1 (0.70) ZDHHC20ZDHHC2ALDH1A1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180346629-A1 Biocompatible polymers and co-polymers, and uses thereof GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2018-12-06 — — US claimed
EP-0606742-B1 Bile acid sequestrant ROHM & HAAS (US) 1997-11-19 — — EP claimed
EP-0425436-B1 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA GEIGY AG (CH) 1996-12-27 — — EP claimed
US-5519069-A INTERPENETRATING POLYMER NETWORK, TWO CROSSLINKERS, PRECISION CASTING PILKINGTON BARNES HIND, INC. (US) 1996-05-21 — — US claimed
US-5451397-A Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels ROHM AND HAAS COMPANY (US) 1995-09-19 — — US claimed
EP-0606742-A1 Bile acid sequestrant ROHM AND HAAS COMPANY (US) 1994-07-20 — — EP claimed
US-5079319-A Contact Lenses CIBA-GEIGY CORPORATION (US) 1992-01-07 — — US claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 — — EP claimed
US-4289695-A REACTION OF A PHENICILLIN WITH AN N-CHLORO HALOGENATING AGENT IN PRESENCE OF A CROSSLINKED POLYVINYLPYRIDINE ELI LILLY AND COMPANY (US) 1981-09-15 — — US claimed
US-20230280332-A1 Methods for Isolating Immune Binding Proteins Augmenta Bioworks, Inc. (US) 2023-09-07 — — US disclosed
US-11662341-B2 Methods for isolating immune binding proteins Augmenta Bioworks, Inc. (US) 2023-05-30 — — US disclosed
US-20220380746-A1 Methods for Making Gel Beads and Core and Shell Beads with a Cell Augmenta Bioworks, Inc. (US) 2022-12-01 — — US disclosed
EP-3941631-A1 ISOLATION OF SINGLE CELLS AND USES THEREOF Augmenta Bioworks, Inc. (US) 2022-01-26 — — EP disclosed
US-20200385785-A1 COMPOSITIONS AND METHODS FOR BARCODING ROOTPATH GENOMICS, INC. 2020-12-10 — — US disclosed
EP-0011370-B1 PROCESS FOR PREPARING 2-CHLOROSULFINYL-AZETIDINONES ELI LILLY AND COMPANY (US) 1982-04-28 — — EP disclosed
US-4289695-A REACTION OF A PHENICILLIN WITH AN N-CHLORO HALOGENATING AGENT IN PRESENCE OF A CROSSLINKED POLYVINYLPYRIDINE ELI LILLY AND COMPANY (US) 1981-09-15 — — US disclosed
EP-0015345-A1 Process for preparing N-chloroimides ELI LILLY AND COMPANY (US) 1980-09-17 — — EP disclosed
EP-0011370-A1 Process for preparing 2-chlorosulfinyl-azetidinones ELI LILLY AND COMPANY (US) 1980-05-28 — — EP disclosed
US-4152508-A OXYGEN PERMEABILITY, DIMENSIONAL STABILITY POLYMER TECHNOLOGY CORPORATION (US) 1979-05-01 — — US disclosed
US-3953408-A LITHOGRAPHIC PLATES ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180346629-A1 Biocompatible polymers and co-polymers, and uses thereof ARG1, CRYAA, COL1A1 ZDHHC20 3525/4885ZDHHC2 4217/4885ALDH1A1 2924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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