Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632334 | 1.00 | TDP1 (0.56) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL632612 | 1.00 | TDP1 (0.56) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL7447818 | 0.98 | KCNH3 (0.54) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL2388601 | 0.83 | TDP1 (0.52) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL2386760 | 0.83 | TDP1 (0.52) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL17046082 | 0.80 | TSHR (0.71) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL5176869 | 0.80 | ALDH1A1 (0.52) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL21256944 | 0.80 | ALDH1A1 (0.52) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL172358 | 0.79 | ALDH1A1 (0.77) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL13776661 | 0.79 | ALDH1A1 (0.77) | TDP1TSHRALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116202846-B | Method for identifying artery and vein | 河北医科大学第二医院 | 2024-03-22 | — | — | CN | disclosed |
| CN-116202846-A | Method for identifying artery and vein | 河北医科大学第二医院 | 2023-06-02 | — | — | CN | disclosed |
| EP-4135740-A1 | AEROSOLIZED FORMULATIONS OF HIV PROTEASE INHIBITORS FOR THE TREATMENT OF AIRWAY REFLUX | The Medical College of Wisconsin, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021212022-A1 | AEROSOLIZED FORMULATIONS OF HIV PROTEASE INHIBITORS FOR THE TREATMENT OF AIRWAY REFLUX | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2021-10-21 | — | — | WO | disclosed |
| CN-107365368-B | Asperphenamate synthesis related protein, coding gene and application thereof | 中国科学院微生物研究所 | 2020-09-08 | — | — | CN | disclosed |
| EP-2475361-B1 | N-SUBSTITUTED BENZENEPROPANAMIDES FOR USE IN THE TREATMENT OF PAIN AND INFLAMMATION | NOVAREMED LTD (IL) | 2019-11-06 | — | — | EP | disclosed |
| US-20160317479-A1 | METHOD OF TREATING OR PREVENTING PAIN | NOVAREMED LTD. (IL) | 2016-11-03 | — | — | US | disclosed |
| EP-1750691-B1 | COMPOUNDS FOR TREATMENT OF AIDS AND OTHER DISEASES | NOVAREMED LTD (IL) | 2016-08-10 | — | — | EP | disclosed |
| US-9199917-B2 | N-substituted benzenepropanamide or benzenepropenamide derivatives for use in the treatment of pain and inflammation | NOVAREMED LIMITED (IL) | 2015-12-01 | — | — | US | disclosed |
| EP-2655344-B1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USE | UNIV CATHOLIQUE LOUVAIN (BE) | 2015-11-25 | — | — | EP | disclosed |
| US-20020156217-A1 | Poly (phosphonoarylacetylene and chiral sensor comprising the same | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2002-10-24 | — | — | US | disclosed |
| EP-1231227-A1 | POLY(PHOSPHONOARYLACETYLENE) AND CHIRAL SENSOR COMPRISING THE SAME | Japan Science and Technology Corporation (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001096278-A2 | A NOVEL PROCESS FOR PREPARING SALMETEROL | GLAXO GROUP LIMITED (GB) | 2001-12-20 | — | — | WO | disclosed |
| EP-1073638-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054304-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |
| US-5846942-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| US-5593967-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0547178-A4 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER LAMBERT CO (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0547178-A1 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004045-A1 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160317479-A1 | METHOD OF TREATING OR PREVENTING PAIN | OPRL1, CALCA, CHRM1 | TDP1 3366/4885TSHR 2742/4885ALDH1A1 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.