Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632333 | 1.00 | TDP1 (0.56) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL632612 | 1.00 | TDP1 (0.56) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL7447818 | 0.98 | KCNH3 (0.54) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL2388601 | 0.83 | TDP1 (0.52) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL2386760 | 0.83 | TDP1 (0.52) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL17046082 | 0.80 | TSHR (0.71) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL5176869 | 0.80 | ALDH1A1 (0.52) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL21256944 | 0.80 | ALDH1A1 (0.52) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL172358 | 0.79 | ALDH1A1 (0.77) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL13776661 | 0.79 | ALDH1A1 (0.77) | TDP1TSHRALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101199918-A | Process for preparing polymer microporous membrane and usage of same | SHANGHAI SHILONG SCIENCE & TEC (CN) | 2008-06-18 | — | — | CN | claimed |
| CN-117417526-A | Conductive polymer coated super-crosslinked porous polymer wave absorber and preparation method thereof | 烟台哈尔滨工程大学研究院 | 2024-01-19 | — | — | CN | disclosed |
| US-20210379574-A1 | MULTI-FUNCTIONALIZED HOLLOW FIBER ORGANOCATALYSTS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2021-12-09 | — | — | US | disclosed |
| CN-105131041-A | Novel triphenyl organic bismuth (V) complex catalyst, preparation method thereof, and catalysis application thereof in nitrogen-containing compounds | UNIV HUNAN | 2015-12-09 | — | — | CN | disclosed |
| US-8586617-B2 | Aminomethyl-4-imidazoles | HOFFMANN-LA ROCHE INC. (US) | 2013-11-19 | — | — | US | disclosed |
| EP-2076497-B1 | AMINOMETHYL-4-IMIDAZOLES | HOFFMANN LA ROCHE (CH) | 2012-02-22 | — | — | EP | disclosed |
| CN-101199918-A | Process for preparing polymer microporous membrane and usage of same | SHANGHAI SHILONG SCIENCE & TEC (CN) | 2008-06-18 | — | — | CN | disclosed |
| US-20080119535-A1 | AMINOMETHYL-4-IMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-05-22 | — | — | US | disclosed |
| EP-1507511-B1 | PERSONAL CARE COMPOSITIONS WITH HYDROXY AMINE NEUTRALIZED POLYMERS | UNILEVER PLC (GB) | 2006-07-26 | — | — | EP | disclosed |
| EP-1507511-A1 | PERSONAL CARE COMPOSITIONS WITH HYDROXY AMINE NEUTRALIZED POLYMERS | UNILEVER PLC (GB) | 2005-02-23 | — | — | EP | disclosed |
| EP-1507512-A1 | COSMETIC COMPOSITIONS WITH HYDROXY AMINE SALTS OF MALONIC ACID | UNILEVER PLC (GB) | 2005-02-23 | — | — | EP | disclosed |
| US-20040241131-A1 | Compositions containing malonate salts in preventing in-grown hair arising from shaving | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-12-02 | — | — | US | disclosed |
| US-20030228337-A1 | Personal care compositions with hydroxy amine neutralized polymers | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-12-11 | — | — | US | disclosed |
| WO-2003099252-A1 | COSMETIC COMPOSITIONS WITH HYDROXY AMINE SALTS OF MALONIC ACID | UNILEVER PLC (GB) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003099253-A1 | PERSONAL CARE COMPOSITIONS WITH HYDROXY AMINE NEUTRALIZED POLYMERS | UNILEVER PLC (GB) | 2003-12-04 | — | — | WO | disclosed |
| US-20030224023-A1 | Cosmetic compositions with hydroxy amine salts of malonic acid | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-12-04 | — | — | US | disclosed |
| EP-0982333-A1 | Polyurethane formulations based on hydroxylated polybutadiene catalyzed by an imidazole derivative | ELF ATOCHEM S.A. (FR) | 2000-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224023-A1 | Cosmetic compositions with hydroxy amine salts of malonic acid | CUTA, TYR, DDC | TDP1 2123/4885TSHR 3448/4885ALDH1A1 281/4885 |
| US-20030228337-A1 | Personal care compositions with hydroxy amine neutralized polymers | CUTA, PARN, POLH | TDP1 533/4885TSHR 3835/4885ALDH1A1 1635/4885 |
| US-20080119535-A1 | AMINOMETHYL-4-IMIDAZOLES | INMT, HTR4, MC4R | TDP1 1506/4885TSHR 2098/4885ALDH1A1 631/4885 |
| US-20210379574-A1 | MULTI-FUNCTIONALIZED HOLLOW FIBER ORGANOCATALYSTS | HAAO, DCAF1, HPD | TDP1 4150/4885TSHR 4731/4885ALDH1A1 945/4885 |
| US-20040241131-A1 | Compositions containing malonate salts in preventing in-grown hair arising from shaving | DPM1, POLR1C, MSH6 | TDP1 2841/4885TSHR 4651/4885ALDH1A1 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.