SCHEMBL6323663

SCHEMBL6323663

N=Nc1ccc(CO[PH](=O)OCc2ccc(N=N)cc2)cc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9849327 0.78 TRPA1 (0.39) CA2CA9
SCHEMBL742829 0.76 ALDH1A1 (0.46) CA2CA9
SCHEMBL8855401 0.76 IDO1 (0.50) CA2
SCHEMBL4055235 0.74 IDO1 (0.52) CA2CA9
SCHEMBL6020749 0.74 CA2 (0.32) CA2CA9
SCHEMBL5432093 0.74 AGXT (0.52) CA2CA9
SCHEMBL17181662 0.74 IDO1 (0.52) CA2CA9
SCHEMBL17061042 0.74 CYP3A4 (0.52)
SCHEMBL2016123 0.74 IDO1 (0.52) CA2CA9
SCHEMBL10813967 0.74 ERN1 (0.35) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6924361-B1 Phosphopeptide-specific antibodies that are activity specific; methods of production and antibody uses PHOSPHOPROTEOMICS LLC (US) 2005-08-02 US disclosed
EP-0461174-B1 METHOD AND KIT FOR DETERMINING TYROSINE-PHOSPHORYLATING AND DEPHOSPHORYLATING ACTIVITIES FERRING NV (AN) 1994-11-17 EP disclosed
EP-0461174-A1 METHOD AND KIT FOR DETERMINING TYROSINE-PHOSPHORYLATING AND DEPHOSPHORYLATING ACTIVITIES. EURO DIAGNOSTICS BV (NL) 1991-12-18 EP disclosed
WO-1990010234-A1 METHOD AND KIT FOR DETERMINING TYROSINE-PHOSPHORYLATING AND DEPHOSPHORYLATING ACTIVITIES EURO-DIAGNOSTICS B.V. (NL) 1990-09-07 WO disclosed
US-4543439-A Production and use of monoclonal antibodies to phosphotyrosine-containing proteins MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1985-09-24 US disclosed
US-4543439-A Production and use of monoclonal antibodies to phosphotyrosine-containing proteins MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1985-09-24 US disclosed