SCHEMBL6323768

SCHEMBL6323768

CCCNC(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
USP2 O75604 1/20 0.53
KMT2A Q03164 4/20 0.52
KDM4E B2RXH2 1/20 0.52
NAMPT P43490 1/20 0.52
ALDH1A1 P00352 2/20 0.51
GPR55 Q9Y2T6 1/20 0.51
CYP3A4 P08684 1/20 0.50
THRB P10828 1/20 0.50
TSHR P16473 1/20 0.50
NFKB1 P19838 1/20 0.50
HTR2A P28223 1/20 0.50
CYP2C19 P33261 1/20 0.50
ADRA1A P35348 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
GHSR Q92847 1/20 0.50
HDAC3 O15379 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC2 Q92769 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6321364 0.89 CA1 (0.61) LMNAUSP2KMT2AKDM4ENAMPT
SCHEMBL6331436 0.88 ALDH1A1 (0.68) LMNAKMT2AKDM4ENAMPTALDH1A1
SCHEMBL6329987 0.87 FBP1 (0.61) NAMPTALDH1A1
SCHEMBL6323967 0.87 LMNA (0.51) LMNAKMT2AALDH1A1CYP3A4THRB
SCHEMBL7602192 0.86 FBP1 (0.60) LMNAKMT2AKDM4ENAMPTALDH1A1
SCHEMBL6326396 0.84 CA1 (0.52) KMT2AKDM4ENAMPTHDAC3HDAC1
SCHEMBL2290886 0.81 ALDH1A1 (0.72) LMNAKDM4EALDH1A1CYP3A4THRB
SCHEMBL6330129 0.80 L3MBTL1 (0.63) LMNAUSP2KMT2AKDM4EALDH1A1
SCHEMBL8627835 0.80 MAPT (0.66) LMNAKMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL7276663 0.80 LMNA (0.63) LMNAKMT2AALDH1A1NCOR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed