SCHEMBL6329987

SCHEMBL6329987

CCCNC(=O)c1ccc(NC(=O)NS(=O)(=O)c2cccc(C)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 15/20 0.61
NLRP3 Q96P20 1/20 0.51
KCNA1 Q09470 1/20 0.50
KCNAB1 Q14722 1/20 0.50
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
HPGD P15428 1/20 0.49
NAMPT P43490 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6324571 0.90 FBP1 (0.60) FBP1NLRP3KCNA1KCNAB1
SCHEMBL7602192 0.88 FBP1 (0.60) FBP1ALDH1A1NAMPT
SCHEMBL6323768 0.87 LMNA (0.54) ALDH1A1NAMPT
SCHEMBL6321364 0.86 CA1 (0.61) ALDH1A1MAPTNAMPT
SCHEMBL6322058 0.82 FBP1 (0.64) FBP1
SCHEMBL6731776 0.81 FBP1 (0.54) FBP1NLRP3KCNA1KCNAB1MAPT
SCHEMBL6324572 0.81 FBP1 (0.60) FBP1NLRP3ALDH1A1HPGD
SCHEMBL6329251 0.81 NLRP3 (0.57) FBP1NLRP3KCNA1KCNAB1ALDH1A1
SCHEMBL6331436 0.81 ALDH1A1 (0.68) ALDH1A1MAPTNAMPT
SCHEMBL6324690 0.80 LMNA (0.58) KCNA1KCNAB1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed