SCHEMBL6324183

SCHEMBL6324183

CCCNC(=O)c1cccc(NC(=O)NS(=O)(=O)c2ccccc2C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGAV P06756 2/20 0.52
ITGB3 P05106 1/20 0.52
CA1 P00915 4/20 0.49
CA2 P00918 4/20 0.49
CA9 Q16790 4/20 0.49
CA12 O43570 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 2/20 0.45
MMP1 P03956 2/20 0.45
MMP2 P08253 2/20 0.45
MMP9 P14780 2/20 0.45
MMP8 P22894 2/20 0.45
MMP13 P45452 2/20 0.45
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
ALDH1A1 P00352 2/20 0.44
CCKBR P32239 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6326396 0.88 CA1 (0.52) ITGAVITGB3CA1CA2CA9
SCHEMBL6323967 0.85 LMNA (0.51) L3MBTL1MAPTLMNAALDH1A1MEN1
SCHEMBL6324690 0.83 LMNA (0.58) CA1CA2CA9CA12MAPT
SCHEMBL6324571 0.83 FBP1 (0.60) LMNAGAAMEN1KMT2A
SCHEMBL6331689 0.82 RAB9A (0.61) CA1CA2CA9CA12MAPT
SCHEMBL6331093 0.82 ALDH1A1 (0.58) CA1CA2CA9CA12MAPT
SCHEMBL6326503 0.82 CA1 (0.55) CA1CA2CA9CA12MMP1
SCHEMBL6324438 0.81 IDH1 (0.60) CA1CA2CA9CA12MAPT
SCHEMBL6331865 0.80 LMNA (0.62) CA1CA2CA9CA12L3MBTL1
SCHEMBL6329425 0.80 SMN1; SMN2 (0.58) CA1CA2CA9CA12MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed