SCHEMBL6324696

SCHEMBL6324696

CN(C(=O)OCC1c2ccccc2-c2ccccc21)[C@@](C)(C(=O)O)c1ccc2ccccc2c1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.41
FABP7 O15540 2/20 0.41
EPHX2 P34913 1/20 0.37
MDM4 O15151 1/20 0.37
TP53 P04637 1/20 0.37
KMT2A Q03164 2/20 0.37
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
KCNH2 Q12809 1/20 0.36
CASP3 P42574 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29855332 0.84 FABP5 (0.40) FABP5FABP7EPHX2MDM4TP53
SCHEMBL2498935 0.80 ALDH1A1 (0.40) KMT2ACYP3A4CYP2D6SLC6A2SLC6A4
SCHEMBL118230 0.79 FABP5 (0.46) FABP5FABP7EPHX2MDM4TP53
SCHEMBL29709499 0.79 FABP5 (0.46) FABP5FABP7EPHX2MDM4TP53
SCHEMBL29908653 0.79 FABP5 (0.46) FABP5FABP7EPHX2MDM4TP53
SCHEMBL27488088 0.77 FABP5 (0.41) FABP5FABP7EPHX2MDM4TP53
SCHEMBL7951407 0.77 SLC6A4 (0.40) KMT2ACYP3A4CYP2D6SLC6A2SLC6A4
SCHEMBL25657461 0.75 KMT2A (0.47) FABP5FABP7EPHX2MDM4TP53
SCHEMBL5171440 0.74 FABP5 (0.38) FABP5FABP7EPHX2MDM4TP53
SCHEMBL25185748 0.74 FABP5 (0.42) FABP5FABP7EPHX2MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6939880-B2 Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 2005-09-06 US disclosed
US-20030055261-A1 Compounds with growth hormone releasing properties HELSINN THERAPEUTICS (U.S.), INC. 2003-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055261-A1 Compounds with growth hormone releasing properties GHRHR, GHSR, IGFBP1 FABP5 692/4885FABP7 215/4885EPHX2 3759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.