Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2280446 | 0.82 | HTT (0.58) | HSD11B1ALDH1A1MAPK1HTTTP53 | |
| SCHEMBL8224812 | 0.79 | HSD11B1 (0.40) | HSD11B1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2695402 | 0.78 | ESR1 (0.55) | HSD11B1ALDH1A1HTTCES1CA12 | |
| SCHEMBL2278952 | 0.78 | MAPK1 (0.54) | ALDH1A1KDM4EMAPK1HTTTP53 | |
| SCHEMBL1355880 | 0.75 | ESR1 (0.36) | HSD11B1KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL5109984 | 0.75 | L3MBTL1 (0.36) | HSD11B1ALDH1A1HSD17B10MAPK1HTT | |
| SCHEMBL6320855 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDALOX15HSD17B10 | |
| SCHEMBL2995730 | 0.73 | L3MBTL1 (0.49) | HSD11B1ALDH1A1HSD17B10MAPK1TDP1 | |
| SCHEMBL4059596 | 0.72 | MMP2 (0.47) | MAPK1RORCPSEN1PSEN2APH1B | |
| SCHEMBL10907104 | 0.72 | CA12 (0.48) | ALDH1A1KDM4EHPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |