SCHEMBL2695402

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7462661	0.82	POLB (0.57)	ESR1POLBCYP3A4CYP2D6CYP2C9
	SCHEMBL16178528	0.81	ESR1 (0.46)	ESR1POLBCYP3A4CYP2D6CYP2C9
	SCHEMBL10927434	0.80	ESR1 (0.53)	ESR1POLBHSD11B1LMNAALDH1A1
	SCHEMBL7470800	0.79	POLB (0.58)	ESR1POLBCYP3A4CYP2D6CYP2C9
	SCHEMBL2993431	0.78	ALDH1A1 (0.43)	ESR1CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL5191774	0.78	ESR1 (0.77)	ESR1HSD11B1ALDH1A1KMT2ACA12
	SCHEMBL1355880	0.78	ESR1 (0.36)	ESR1POLBCYP3A4CYP2D6CYP2C9
	SCHEMBL6325501	0.78	HSD11B1 (0.47)	HSD11B1ALDH1A1TP53SMN1; SMN2CES1
	SCHEMBL8224812	0.78	HSD11B1 (0.40)	ESR1HSD11B1LMNANR3C2CES1
	SCHEMBL4433011	0.77	LMNA (0.41)	ESR1POLBCYP3A4NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.