SCHEMBL6325782

SCHEMBL6325782

CC(NS(=O)(=O)c1ccccc1)C(=O)Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADAMTS4 O75173 2/20 0.61
ALDH1A1 P00352 4/20 0.56
HSD17B10 Q99714 3/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.51
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.51
TSHR P16473 1/20 0.51
MMP2 P08253 5/20 0.50
MMP13 P45452 4/20 0.50
MMP3 P08254 3/20 0.50
MMP1 P03956 3/20 0.50
MMP9 P14780 3/20 0.50
SLC1A3 P43003 2/20 0.50
SLC1A2 P43004 2/20 0.50
SLC1A1 P43005 2/20 0.50
MMP7 P09237 2/20 0.50
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL790069 0.85 ADAMTS4 (0.81) ADAMTS4ALDH1A1HSD17B10L3MBTL1SMN1; SMN2
SCHEMBL702794 0.85 ADAMTS4 (0.81) ADAMTS4ALDH1A1HSD17B10L3MBTL1SMN1; SMN2
SCHEMBL702793 0.85 ADAMTS4 (0.81) ADAMTS4ALDH1A1HSD17B10L3MBTL1SMN1; SMN2
SCHEMBL3884127 0.84 MMP2 (0.57) ADAMTS4ALDH1A1MMP2MMP13MMP3
SCHEMBL5734780 0.84 TSHR (0.56) ADAMTS4ALDH1A1HSD17B10SMN1; SMN2LMNA
SCHEMBL3884130 0.84 MMP2 (0.57) ADAMTS4ALDH1A1MMP2MMP13MMP3
SCHEMBL5734792 0.84 TSHR (0.56) ADAMTS4ALDH1A1HSD17B10SMN1; SMN2LMNA
SCHEMBL28502922 0.84 TSHR (0.56) ADAMTS4ALDH1A1HSD17B10SMN1; SMN2LMNA
SCHEMBL17318887 0.83 ADAMTS4 (0.62) ADAMTS4ALDH1A1HSD17B10L3MBTL1SMN1; SMN2
SCHEMBL3687103 0.82 ADAMTS4 (0.61) ADAMTS4ALDH1A1HSD17B10L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050239107-A1 Trapped photochromes and thermochromes and uses for chromogenic detection, including detection of airborne contaminants MERIS INVESTMENT INC. 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050239107-A1 Trapped photochromes and thermochromes and uses for chromogenic detection, including detection of airborne contaminants CBX3, CBX6, CBX2 ADAMTS4 4679/4885ALDH1A1 423/4885HSD17B10 1179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.