Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 9/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | WRN | Q14191 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445978 | 0.87 | SNCA (0.47) | RAB9ASMN1; SMN2HTTKDM4EPOLB | |
| SCHEMBL6324529 | 0.87 | MAPT (0.52) | BLMRAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL6323345 | 0.87 | RAB9A (0.50) | BLMRAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL6329444 | 0.87 | MEN1 (0.58) | BLMRAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL6329453 | 0.86 | BLM (0.52) | BLMRAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL6323159 | 0.86 | BLM (0.57) | BLMRAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL6325012 | 0.86 | RAB9A (0.55) | BLMRAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL6325969 | 0.84 | BLM (0.45) | BLMRAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL6324404 | 0.83 | CBS (0.54) | BLMRAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL6329503 | 0.83 | MAPT (0.58) | RAB9ASMN1; SMN2HTTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | BRISTOL-MYERS SQUIBB CO. | 2005-06-09 | — | — | US | claimed |
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | BRISTOL-MYERS SQUIBB CO. | 2005-06-09 | — | — | US | disclosed |
| US-20050113438-A1 | Substituted indoles | WYETH (US) | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | SERPINE1, SERPINC1, SERPINB1 | BLM 2929/4885RAB9A 3129/4885SMN1; SMN2 3158/4885 |
| US-20050113438-A1 | Substituted indoles | IDO2, IDO1, INMT | BLM 3187/4885RAB9A 3184/4885SMN1; SMN2 3610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.