Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325847 | 0.87 | MAPT (0.64) | MAPTLMNAKDM4EL3MBTL1NPC1 | |
| SCHEMBL3866097 | 0.86 | MAPT (0.57) | MAPTLMNAKDM4EL3MBTL1NPC1 | |
| SCHEMBL6321338 | 0.86 | MAPT (0.64) | MAPTLMNAKDM4EL3MBTL1NPC1 | |
| SCHEMBL6328277 | 0.86 | MAPT (0.64) | MAPTLMNAKDM4EL3MBTL1NPC1 | |
| SCHEMBL6318934 | 0.83 | MAPT (0.78) | MAPTLMNAKDM4EL3MBTL1NPC1 | |
| SCHEMBL4447937 | 0.83 | MAPT (0.54) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6319805 | 0.83 | MAPT (0.68) | MAPTLMNAKDM4EL3MBTL1NPC1 | |
| SCHEMBL6202777 | 0.83 | MAPT (0.64) | MAPTLMNAKDM4EL3MBTL1NPC1 | |
| SCHEMBL14207930 | 0.82 | DRD4 (0.50) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4454647 | 0.81 | MAPT (0.53) | MAPTKDM4EL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| US-6927225-B2 | Fungicidal 2-pyridyl alkyl amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2005-08-09 | — | — | US | disclosed |
| US-20030022902-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | RICKS MICHAEL J (US) | 2003-01-30 | — | — | US | disclosed |
| US-20030018052-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | RICKS MICHAEL J (US) | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018052-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | NAT1, CYP4X1, CYP1A1 | MAPT 1375/4885LMNA 2000/4885KDM4E 515/4885 |
| US-20030022902-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | NAT1, CYP1A1, CYP4X1 | MAPT 1704/4885LMNA 2149/4885KDM4E 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.