Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | MGMT | P16455 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830938 | 0.82 | TSHR (0.50) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL6328998 | 0.82 | POLB (0.38) | MAPK1POLBHSD17B10EGFRCDK1 | |
| SCHEMBL6328488 | 0.80 | HTT (0.41) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL21118379 | 0.77 | LMNA (0.42) | LTA4HKCNH2TSHRLMNACYP2C9 | |
| SCHEMBL2452622 | 0.77 | LTA4H (0.39) | LTA4HKCNH2TSHRLMNACYP2C9 | |
| SCHEMBL27746583 | 0.74 | LTA4H (0.38) | LTA4HKCNH2TSHRLMNACYP2C9 | |
| SCHEMBL20204037 | 0.74 | LTA4H (0.38) | LTA4HKCNH2TSHRLMNACYP2C9 | |
| SCHEMBL246630 | 0.72 | CYP2C9 (0.46) | LTA4HKCNH2TSHRLMNACYP2C9 | |
| Clodinafop Propargyl SCHEMBL28325546 | 0.70 | L3MBTL1 (0.57) | LTA4HKCNH2TSHRLMNACYP2C9 | |
| SCHEMBL2287859 | 0.70 | SLC6A4 (0.56) | TSHRLMNAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107437-A1 | comprising pyridylalkynes used as preemergence and postemergence herbicides | SYNGENTA CROP PROTECTION, INC. | 2005-05-19 | — | — | US | disclosed |
| EP-1453807-A2 | NOVEL HERBICIDES | Syngenta Participations AG (CH) | 2004-09-08 | — | — | EP | disclosed |
| US-20040102325-A1 | Phenylpropynyloxypyridine herbicides | SYNGENTA CROP PROTECTION, INC. | 2004-05-27 | — | — | US | disclosed |
| WO-2003104206-A2 | HERBICIDALLY ACTIVE HETEROCYCLYLALKYNES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-12-18 | — | — | WO | disclosed |
| EP-1370140-A1 | PHENYLPROPYNYLOXYPYRIDINE HERBICIDES | Syngenta Participations AG (CH) | 2003-12-17 | — | — | EP | disclosed |
| WO-2003050087-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-06-19 | — | — | WO | disclosed |
| WO-2002028182-A1 | PHENYLPROPYNYLOXYPYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102325-A1 | Phenylpropynyloxypyridine herbicides | DDT, GSTM1, CYP4X1 | P2RX3 108/4885P2RX2 156/4885LTA4H 4097/4885 |
| US-20050107437-A1 | comprising pyridylalkynes used as preemergence and postemergence herbicides | DDT, CHRM1, CYP4X1 | P2RX3 96/4885P2RX2 112/4885LTA4H 2373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.