SCHEMBL28959040

SCHEMBL28959040

NCCN(C(=O)c1ccc(F)cc1)C(=O)c1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ROCK1 Q13464 1/20 0.46
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
KMT2A Q03164 1/20 0.44
RAB9A P51151 2/20 0.42
PTPN1 P18031 1/20 0.42
NPC1 O15118 1/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CYP3A4 P08684 1/20 0.41
MCHR1 Q99705 1/20 0.40
BCL2L1 Q07817 1/20 0.39
BAD Q92934 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
NSD2 O96028 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28907322 0.86 HDAC3 (0.44) ROCK1CES2CES1KMT2ARAB9A
SCHEMBL28507772 0.86 HDAC3 (0.44) ROCK1CES2CES1KMT2ARAB9A
SCHEMBL28862080 0.86 HDAC3 (0.44) ROCK1CES2CES1KMT2ARAB9A
SCHEMBL9775729 0.82 PHLPP2 (0.42) KMT2ARAB9ANPC1CYP3A4
SCHEMBL633271 0.80 ADRA2C (0.56) CES2CES1KMT2ACYP3A4HDAC1
SCHEMBL11220850 0.77 CA1 (0.52) CES2CES1CA1CA2HDAC3
SCHEMBL8661374 0.77 LOXL2 (0.56) KMT2ARAB9ANPC1CA1CA2
SCHEMBL25390111 0.73 SCN1A (0.47) CA1CA2HDAC3HDAC1
SCHEMBL2777453 0.71 RAB9A (0.53) CES2CES1KMT2ARAB9APTPN1
SCHEMBL4831308 0.69 CES2 (0.50) CES2CES1KMT2ARAB9ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716664-B Semi-aromatic copolymerized polyarylether amide, complex thereof and preparation method thereof 四川大学 2023-02-28 CN disclosed
CN-114716664-A Semi-aromatic copolymerized polyarylether amide, complex thereof and preparation method thereof 四川大学 2022-07-08 CN disclosed