Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162402 | 0.83 | LMNA (0.41) | PHLPP2LMNATSHRCYP1A2CYP3A4 | |
| SCHEMBL28959040 | 0.82 | ROCK1 (0.46) | CYP3A4KMT2ANPC1RAB9A | |
| SCHEMBL633271 | 0.82 | ADRA2C (0.56) | TSHRCYP3A4CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL11220850 | 0.78 | CA1 (0.52) | MAPTKDM4EPKMHPGDPARP10 | |
| SCHEMBL8661374 | 0.78 | LOXL2 (0.56) | TSHRALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL25390111 | 0.74 | SCN1A (0.47) | ADRA2CSCN1ASCN2ASCN3A | |
| SCHEMBL12156519 | 0.74 | LIMK2 (0.62) | CYP3A4KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL11718165 | 0.72 | NPC1 (0.49) | LMNATSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11717608 | 0.72 | NPC1 (0.49) | LMNATSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11711619 | 0.72 | NPC1 (0.49) | LMNATSHRCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059683-A | Dyeing paper, textiles, leather | SANDOZ LTD. (CH) | 1991-10-22 | — | — | US | disclosed |
| EP-0341214-A2 | Basic 6-hydroxypyrid-2-one compounds | SANDOZ AG (CH) | 1989-11-08 | — | — | EP | disclosed |