SCHEMBL6334237

SCHEMBL6334237

Nc1nc(-c2ccc(-c3ccccc3)cc2)nc(-c2ccc(-c3ccccc3)cc2)n1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 6/20 0.82
ADORA2A P29274 5/20 0.82
ADORA3 P0DMS8 2/20 0.82
ADORA2B P29275 2/20 0.82
POLB P06746 1/20 0.82
ALOX15 P16050 1/20 0.63
TSHR P16473 1/20 0.63
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
ALDH1A1 P00352 2/20 0.61
MAPT P10636 2/20 0.61
HPGD P15428 2/20 0.61
HSP90AA1 P07900 1/20 0.60
HSP90AB1 P08238 1/20 0.60
CYP3A4 P08684 1/20 0.56
TAAR1 Q96RJ0 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18057759 1.00 ADORA1 (0.82) ADORA1ADORA2AADORA3ADORA2BPOLB
SCHEMBL6977514 0.95 ADORA1 (0.91) ADORA1ADORA2AADORA3ADORA2BPOLB
SCHEMBL3424387 0.95 ADORA2A (0.90) ADORA1ADORA2AADORA3ADORA2BPOLB
SCHEMBL24914941 0.92 ADORA2A (0.69) ADORA1ADORA2AADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL28634836 0.90 ADORA2A (1.00) ADORA1ADORA2AADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL27898 0.90 ADORA2A (1.00) ADORA1ADORA2AADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL917182 0.90 ADORA2A (1.00) ADORA1ADORA2AADORA3ADORA2BPOLB
SCHEMBL18057757 0.90 ADORA2A (0.67) ADORA1ADORA2AADORA3ADORA2BPOLB
SCHEMBL24914940 0.90 ADORA2A (0.67) ADORA1ADORA2AADORA3ADORA2BPOLB
SCHEMBL18463352 0.89 ADORA2A (0.72) ADORA1ADORA2AADORA3ADORA2BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3908576-A1 A PROCESS FOR THE PREPARATION OF UV ABSORBERS BASF SE (DE) 2021-11-17 EP disclosed
EP-3908633-A1 A PROCESS FOR THE PREPARATION OF TRIAZINE INTERMEDIATES AND A PROCESS FOR THE PREPARATION OF UV ABSORBERS THEREOF BASF SE (DE) 2021-11-17 EP disclosed
EP-3799143-A1 FIRST AND SECOND ORGANIC SEMICONDUCTOR LAYER AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME Novaled GmbH (DE) 2021-03-31 EP disclosed
WO-2020144094-A1 A PROCESS FOR THE PREPARATION OF UV ABSORBERS BASF SE (DE) 2020-07-16 WO disclosed
WO-2020144094-A1 A PROCESS FOR THE PREPARATION OF UV ABSORBERS BASF SE (DE) 2020-07-16 WO disclosed
WO-2020144093-A1 A PROCESS FOR THE PREPARATION OF TRIAZINE INTERMEDIATES AND A PROCESS FOR THE PREPARATION OF UV ABSORBERS THEREOF BASF SE (DE) 2020-07-16 WO disclosed
US-10680183-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-09 US disclosed
US-20160260909-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-08 US disclosed
US-20160260909-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-08 US disclosed
US-6919454-B2 Biphenyl-substituted triazines CIBA SPECIALTY CHEMICALS CORP. (US) 2005-07-19 US disclosed
US-20050019281-A1 Biphenyl-substituted triazines FLETCHER IAN JOHN (CH) 2005-01-27 US disclosed
US-6841670-B2 High thermal stability, are used as stabilizers for organic polymers to counter damage thereto caused by light, oxygen and heat, as light stabilizers for textile fiber materials and as sunscreens for the human skin. CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-01-11 US disclosed
US-20030045444-A1 Biphenyl-substituted triazines FLETCHER IAN JOHN (CH) 2003-03-06 US disclosed
US-6468958-B2 LIGHT, OXYGEN AND HEAT RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION 2002-10-22 US disclosed
EP-0815089-B1 BIPHENYL-SUBSTITUTED TRIAZINES AS LIGHT STABILIZER CIBA SC HOLDING AG (CH) 2002-09-25 EP disclosed
US-20010039341-A1 Biphenyl-Substituted Triazines FLETCHER IAN JOHN (CH) 2001-11-08 US disclosed
US-6255483-B1 USEFUL AS LIGHT STABILIZERS FOR TEXTILE FIBER MATERIALS AND SUNSCREENS FOR HUMAN SKIN CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-03 US disclosed
EP-0815089-A1 BIPHENYL-SUBSTITUTED TRIAZINES AS LIGHT STABILIZER Ciba SC Holding AG (CH) 1998-01-07 EP disclosed
WO-1996028431-A1 BIPHENYL-SUBSTITUTED TRIAZINES AS LIGHT STABILIZER CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050019281-A1 Biphenyl-substituted triazines TYR, AHR, CUTA ADORA1 3623/4885ADORA2A 3231/4885ADORA3 4147/4885
US-10680183-B2 Organic electroluminescent materials and devices PNMT, CYCS, NES ADORA1 1745/4885ADORA2A 1546/4885ADORA3 481/4885
US-20030045444-A1 Biphenyl-substituted triazines TYR, CYP1B1, NFE2L2 ADORA1 2423/4885ADORA2A 3364/4885ADORA3 4137/4885
US-20010039341-A1 Biphenyl-Substituted Triazines TYR, CYP1B1, NFE2L2 ADORA1 2423/4885ADORA2A 3364/4885ADORA3 4137/4885
US-20160260909-A1 Organic Electroluminescent Materials and Devices PNMT, CYCS, NES ADORA1 1745/4885ADORA2A 1546/4885ADORA3 481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.