Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.55 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467089 | 0.88 | ABCG2 (0.56) | IMPDH2IMPDH1ABCG2ALDH1A1GPR3 | |
| SCHEMBL7714636 | 0.84 | IMPDH2 (0.56) | IMPDH2IMPDH1ABCG2ALDH1A1GPR3 | |
| SCHEMBL4886902 | 0.83 | IMPDH2 (0.47) | IMPDH2IMPDH1ABCG2ALDH1A1GPR3 | |
| SCHEMBL329711 | 0.79 | KIF11 (0.50) | ALDH1A1GPR3HSD17B10TTRGABRP | |
| SCHEMBL9625037 | 0.77 | KIF11 (0.49) | ALDH1A1GPR3HSD17B10TTRGABRP | |
| Hydrochloric Acid SCHEMBL28097170 | 0.77 | KIF11 (0.49) | ALDH1A1GPR3HSD17B10TTRGABRP | |
| Carbazole SCHEMBL742559 | 0.76 | ALDH1A1 (0.70) | IMPDH2IMPDH1ALDH1A1GPR3HSD17B10 | |
| Carbazole SCHEMBL10650068 | 0.76 | ALDH1A1 (0.70) | IMPDH2IMPDH1ALDH1A1GPR3HSD17B10 | |
| Formaldehyde SCHEMBL28971933 | 0.76 | KIF11 (0.51) | ALDH1A1GPR3HSD17B10TTRGABRP | |
| SCHEMBL877447 | 0.75 | IMPDH2 (0.54) | IMPDH2IMPDH1ALDH1A1GPR3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091053-B1 | OPTICAL FLUORESCENT IMAGING USING CYANINE DYES | LI COR INC (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-2419478-B1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI COR INC (US) | 2018-02-28 | — | — | EP | disclosed |
| EP-2630196-B1 | CYANINE DYES AND THEIR CONJUGATES | LI COR INC (US) | 2017-09-06 | — | — | EP | disclosed |
| EP-3091053-A1 | OPTICAL FLUORESCENT IMAGING USING CYANINE DYES | LI-COR, INC. (US) | 2016-11-09 | — | — | EP | disclosed |
| US-9408924-B2 | Bioconjugates of cyanine dyes | LI-COR, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| EP-2035505-B1 | OPTICAL FLUORESCENT IMAGING USING CYANINE DYES | LI COR INC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9248203-B2 | Fluorescent imaging with substituted cyanine dyes | LI-COR, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-9089603-B2 | Fluorescent imaging with substituted cyanine dyes | LI-COR, INC. (US) | 2015-07-28 | — | — | US | disclosed |
| US-20150119553-A1 | BIOCONJUGATES OF CYANINE DYES | LI-COR, INC. | 2015-04-30 | — | — | US | disclosed |
| US-8927719-B2 | Cyanine dyes and their conjugates | LI-COR, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-7504089-B2 | Cyanine dyes | LI-COR, INC. (US) | 2009-03-17 | — | — | US | disclosed |
| WO-2007136996-A1 | OPTICAL FLUORESCENT IMAGING USING CYANINE DYES | LI-COR, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| US-20060280688-A1 | OPTICAL FLUORESCENT IMAGING | LI-COR, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060063247-A1 | Cyanine dyes | LI-COR, INC. (US) | 2006-03-23 | — | — | US | disclosed |
| US-6995274-B2 | Cyanine dyes | LI-COR, INC. (US) | 2006-02-07 | — | — | US | disclosed |
| EP-1319047-B1 | CYANINE DYES | LI COR INC (US) | 2006-01-04 | — | — | EP | disclosed |
| US-20040014981-A1 | Cyanine dyes | LI-COR, INC. | 2004-01-22 | — | — | US | disclosed |
| EP-1319047-A1 | CYANINE DYES | Li-Cor, Inc. (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024815-A1 | CYANINE DYES | LI-COR, INC. (US) | 2002-03-28 | — | — | WO | disclosed |
| US-5380456-A | Aromatic aminosulfonic acid, liquid bleach | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1995-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060280688-A1 | OPTICAL FLUORESCENT IMAGING | FCGR2A, CD69, FOLR1 | IMPDH2 2251/4885IMPDH1 2384/4885ABCG2 397/4885 |
| US-20040014981-A1 | Cyanine dyes | IK, CBR3, MRPS35 | IMPDH2 4409/4885IMPDH1 3904/4885ABCG2 1610/4885 |
| US-20060063247-A1 | Cyanine dyes | MRPS35, CBR3, IK | IMPDH2 4236/4885IMPDH1 4078/4885ABCG2 1279/4885 |
| US-20150119553-A1 | BIOCONJUGATES OF CYANINE DYES | FCGR3B, FCGR2A, HCCS | IMPDH2 3551/4885IMPDH1 3964/4885ABCG2 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.