Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633429 | 0.79 | ALDH1A1 (0.47) | PRNPNPSR1SMN1; SMN2 | |
| SCHEMBL27908746 | 0.72 | CCR1 (0.42) | HTTNPSR1KDM4ESMN1; SMN2DYRK1A | |
| SCHEMBL30059116 | 0.72 | HTT (0.41) | LMNAPRNPHPGDHTTNPSR1 | |
| SCHEMBL21403775 | 0.72 | HTT (0.41) | LMNAPRNPHPGDHTTNPSR1 | |
| SCHEMBL534655 | 0.70 | HTT (0.40) | LMNAPRNPHPGDHTTNPSR1 | |
| SCHEMBL1927586 | 0.70 | ESR1 (0.33) | LMNAPRNPHPGDHTTNPSR1 | |
| SCHEMBL19783063 | 0.68 | NSD1 (0.37) | LMNAPRNPHPGDHTTNPSR1 | |
| SCHEMBL21989013 | 0.67 | DYRK1A (0.35) | HPGDHTTNPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL23905532 | 0.67 | KDM4E (0.56) | LMNAPRNPHPGDHTTNPSR1 | |
| SCHEMBL20176008 | 0.67 | LMNA (0.40) | LMNAPRNPHPGDHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183637-A | Quinoline derivatives and use thereof as fungicides | SYNGENTA CROP PROT INC | 2013-07-03 | — | — | CN | disclosed |
| US-8415272-B2 | Quinoline derivatives and their use as fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-09 | — | — | US | disclosed |
| CN-101910135-B | Quinoline derivatives and their use as fungicides | SYNGENTA PARTICIPATIONS AG | 2013-03-13 | — | — | CN | disclosed |
| EP-2231614-B1 | Quinoline derivatives and their use as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2012-02-22 | — | — | EP | disclosed |
| CN-101910135-A | Quinoline derivatives and their use as fungicides | SYNGENTA PARTICIPATIONS AG | 2010-12-08 | — | — | CN | disclosed |
| US-20100280068-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| EP-2231614-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009087098-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280068-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A1, CYP3A7, CYP1A2 | LMNA 4023/4885PRNP 3769/4885HPGD 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.