Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509059 | 0.84 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2USP2HTTKMT2A | |
| SCHEMBL26817995 | 0.82 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2USP2KMT2AMEN1 | |
| SCHEMBL28539623 | 0.80 | L3MBTL1 (0.60) | ALDH1A1KMT2ARAB9AMEN1CA12 | |
| SCHEMBL2627764 | 0.79 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL760439 | 0.78 | MMP1 (0.67) | ALDH1A1SMN1; SMN2KMT2AMEN1CA1 | |
| SCHEMBL8416902 | 0.78 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2USP2HTTKMT2A | |
| SCHEMBL1997197 | 0.77 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1CA1 | |
| SCHEMBL7090406 | 0.77 | CA2 (0.73) | ALDH1A1SMN1; SMN2KMT2AMEN1CA1 | |
| SCHEMBL4859251 | 0.77 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL4859243 | 0.77 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2USP2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872539-B2 | Analytical system based upon spore germination | ROTMAN M BORIS (US) | 2005-03-29 | — | — | US | disclosed |
| US-6596496-B1 | Detecting preferential particle in sample; obtain spore sample, incubate with germination agent, monitor sample for spore generation | ROTMAN M BORIS (US) | 2003-07-22 | — | — | US | disclosed |
| EP-1131462-A1 | ANALYTICAL SYSTEM BASED UPON SPORE GERMINATION | Rotman, M. Boris (US) | 2001-09-12 | — | — | EP | disclosed |
| US-6228574-B1 | RAPID DETECTION BY MIXING TEST SAMPLE WITH MICROBIAL SPORES AND GERMINOGENIC SOURCE, INCUBATING TO ALLOW ACTIVATION OF SPORES AND ENZYMATIC CONVERSION OF SOURCE TO A GERMINANT AND FOR SPORE GERMINATION, THEN DETECTING GERMINATION | ROTMAN M BORIS (US) | 2001-05-08 | — | — | US | disclosed |
| WO-2000029610-A1 | ANALYTICAL SYSTEM BASED UPON SPORE GERMINATION | ROTMAN M BORIS (US) | 2000-05-25 | — | — | WO | disclosed |