SCHEMBL6340971

SCHEMBL6340971

Fc1ccc(B(c2ccc(F)cc2F)c2ccc(F)cc2F)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
CA3 P07451 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NFE2L2 Q16236 3/20 0.37
IDO1 P14902 2/20 0.37
AGXT P21549 2/20 0.37
KDM4E B2RXH2 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30570479 1.00 ALDH1A1 (0.46) ALDH1A1CES2CES1CA3CA6
SCHEMBL18462883 0.91 ALDH1A1 (0.44) ALDH1A1CES2CES1CA3CA6
SCHEMBL17236452 0.81 ALDH1A1 (0.44) ALDH1A1CES2CES1CA3CA6
SCHEMBL2407958 0.79 ORAI1 (0.44) ALDH1A1CES2CES1CA3CA6
SCHEMBL39406 0.79 CES2 (0.43) ALDH1A1CES2CES1CA3CA6
SCHEMBL29395656 0.79 CES2 (0.43) ALDH1A1CES2CES1CA3CA6
SCHEMBL31047615 0.78 CA3 (0.46) ALDH1A1CES2CES1CA3CA6
SCHEMBL2065706 0.78 CA3 (0.46) ALDH1A1CES2CES1CA3CA6
SCHEMBL26576590 0.75 CES2 (0.40) ALDH1A1CES2CES1CA3CA6
SCHEMBL19726536 0.74 ACHE (0.38) ALDH1A1CA3CA6CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693732-A Acrylic ester polymerization reaction method based on synergistic regulation and control of hydrogen bond and Lewis acid and under synergistic regulation and control of no hydrogen bond and Lewis acid 青岛大学 2023-09-05 CN disclosed
WO-2017016653-A1 NOVEL COMPOUNDS EXHIBITING PHOTOPHYSICAL PROPERTIES UPON FORMATION OF LEWIS ACID-BASE ADDUCTS USING NON-CHELATING BORANES, METHOD FOR PRODUCING THE SAME AND DEVICES INCLUDING THE SAME Universität Heidelberg (DE) 2017-02-02 WO disclosed
US-6864334-B2 Multi-dentate late transition metal catalyst complexes and polymerization methods using those complexes EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2005-03-08 US disclosed
US-20050004334-A1 MULTI-DENTATE LATE TRANSITION METAL CATALYST COMPLEXES AND POLYMERIZATION METHODS USING THOSE COMPLEXES BOFFA LISA SAUNDERS (US) 2005-01-06 US disclosed
US-20040254067-A1 Multi-dentate late transition metal catalyst complexes and polymerization methods using those complexes BOFFA LISA SAUNDERS (US) 2004-12-16 US disclosed
US-6809058-B2 CU, AG AND AU COMPLEXES HAVING A MULTIDENTATE NITROGEN-CONTAINING LIGAND, SUCH AS 2,2':6',2'-TERPYRIDINE, (2,6-BIS(1-PHENYLIMINO) ETHYL)PYRIDINE, 1,4,7-TRIAZACYCLONONANE, OR THEIR SUBSTITUTED DERIVATIVES. EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2004-10-26 US disclosed
US-20030069128-A1 Multi-dentate late transition metal catalyst complexes and polymerization methods using those complexes EXXONMOBIL RESEARCH & ENGINEERING COMPANY 2003-04-10 US disclosed
WO-2003020778-A1 MULTI-DENTATE LATE TRANSITION METAL CATALYST COMPLEXES AND POLYMERIZATION METHODS USING THOSE COMPLEXES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2003-03-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004334-A1 MULTI-DENTATE LATE TRANSITION METAL CATALYST COMPLEXES AND POLYMERIZATION METHODS USING THOSE COMPLEXES NOX3, CA3, KCNN4 ALDH1A1 2611/4885CES2 3328/4885CES1 4355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.