Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2266044 | 0.73 | TLR9 (0.50) | — | |
| Hydrochloric Acid SCHEMBL2263189 | 0.71 | TLR9 (0.48) | — | |
| SCHEMBL6261842 | 0.71 | ADORA2A (0.42) | — | |
| SCHEMBL276859 | 0.71 | ADORA2A (0.42) | — | |
| SCHEMBL28830792 | 0.70 | ADORA2A (0.41) | — | |
| SCHEMBL8175658 | 0.69 | HTR1A (0.36) | HTR1ADRD2 | |
| SCHEMBL13239012 | 0.69 | HTR1A (0.53) | HTR1ADRD2 | |
| SCHEMBL30992343 | 0.69 | HTR1A (0.53) | HTR1ADRD2 | |
| SCHEMBL5277301 | 0.68 | TDP1 (0.52) | HTR1A | |
| SCHEMBL10514753 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090483-A1 | Purine derivatives as kinase inhibitors | ELI LILLY AND COMPANY | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090483-A1 | Purine derivatives as kinase inhibitors | PNP, ADK, NME2 | HTR1A 2208/4885DRD2 4440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.