Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12441564 | 0.86 | MPO (0.47) | MPOKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL21686701 | 0.86 | KDM4E (0.49) | MPOKDM4EALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL6344221 | 0.84 | KDM4E (0.48) | MPOKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL1422420 | 0.84 | GAA (0.46) | MPOKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL6346255 | 0.81 | ALDH1A1 (0.47) | MPOKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL6334855 | 0.79 | HPGD (0.43) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL6343104 | 0.76 | FFAR1 (0.39) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL29079910 | 0.75 | ALDH1A1 (0.51) | MPOKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL28309152 | 0.73 | ALDH1A1 (0.53) | MPOKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL6334920 | 0.72 | FFAR1 (0.41) | ALDH1A1HPGDPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101651-A1 | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis | JOHNSON THEODORE O JR (US) | 2005-05-12 | — | — | US | disclosed |
| US-6872745-B2 | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis | AGOURON PHARMACEUTICALS, INC. (US) | 2005-03-29 | — | — | US | disclosed |
| US-20030225042-A1 | Antipicornaviral compounds and compositions, their uses, and materials for their synthesis | JOHNSON THEODORE O (US) | 2003-12-04 | — | — | US | disclosed |
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |
| EP-1274682-A2 | ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS | AGOURON PHARMACEUTICALS, INC. (US) | 2003-01-15 | — | — | EP | disclosed |
| US-20020006943-A1 | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis | AGOURON PHARMACEUTICALS, INC. | 2002-01-17 | — | — | US | disclosed |
| WO-2001079167-A2 | ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS | AGOURON PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101651-A1 | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis | PRCP, RNPEP, SARNP | MPO 1114/4885KDM4E 3175/4885ALDH1A1 4161/4885 |
| US-20030225042-A1 | Antipicornaviral compounds and compositions, their uses, and materials for their synthesis | RNASEL, SARNP, RNASEH1 | MPO 831/4885KDM4E 2736/4885ALDH1A1 3835/4885 |
| US-20020006943-A1 | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis | PRCP, RNPEP, SERPINB1 | MPO 1021/4885KDM4E 3223/4885ALDH1A1 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.