Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6342914 | 0.86 | KDM4E (0.38) | ALDH1A1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL6342685 | 0.84 | L3MBTL1 (0.41) | ALDH1A1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL6344220 | 0.84 | MEN1 (0.40) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| Water SCHEMBL6344649 | 0.83 | L3MBTL1 (0.41) | ALDH1A1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL6341840 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL6344518 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNAKDM4EHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL6344214 | 0.77 | KDM4E (0.44) | ALDH1A1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL6345004 | 0.77 | KDM4E (0.43) | ALDH1A1LMNAKDM4EHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL6351689 | 0.76 | KDM4E (0.43) | ALDH1A1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL6342440 | 0.75 | CCNE2 (0.39) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949648-B2 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-09-27 | — | — | US | claimed |
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | claimed |
| EP-1270572-A1 | CONDENSED PYRAZOLE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | claimed |
| US-6949648-B2 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20040097539-A1 | To decreases a tissue disorder caused by a compound having cyclooxygenase inhibiting activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-20 | — | — | US | disclosed |
| EP-1380296-A1 | HSP INDUCTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1270572-A1 | CONDENSED PYRAZOLE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097539-A1 | To decreases a tissue disorder caused by a compound having cyclooxygenase inhibiting activity | HSPB1, HSPA1B, HSP90AB1 | ALDH1A1 1952/4885LMNA 2421/4885KDM4E 4355/4885 |
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | PTGS1, PTGIS, IL5 | ALDH1A1 1061/4885LMNA 4847/4885KDM4E 1741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.