Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6351689 | 0.99 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL6344214 | 0.85 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL6342884 | 0.84 | HPGD (0.47) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL6342685 | 0.79 | L3MBTL1 (0.41) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| Water SCHEMBL6344649 | 0.78 | L3MBTL1 (0.41) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL6344723 | 0.77 | ALDH1A1 (0.38) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL6342914 | 0.73 | KDM4E (0.38) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL6341840 | 0.72 | ALDH1A1 (0.40) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL6344518 | 0.72 | ALDH1A1 (0.40) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL6342472 | 0.71 | HPGD (0.50) | KDM4EHSD17B10ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949648-B2 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-09-27 | — | — | US | claimed |
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | claimed |
| EP-1270572-A1 | CONDENSED PYRAZOLE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | claimed |
| US-6949648-B2 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20040097539-A1 | To decreases a tissue disorder caused by a compound having cyclooxygenase inhibiting activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-20 | — | — | US | disclosed |
| EP-1380296-A1 | HSP INDUCTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1270572-A1 | CONDENSED PYRAZOLE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097539-A1 | To decreases a tissue disorder caused by a compound having cyclooxygenase inhibiting activity | HSPB1, HSPA1B, HSP90AB1 | KDM4E 4355/4885HSD17B10 305/4885ALDH1A1 1952/4885 |
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | PTGS1, PTGIS, IL5 | KDM4E 1741/4885HSD17B10 802/4885ALDH1A1 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.