SCHEMBL2009339

SCHEMBL2009339

Cc1cccc(N)c1CO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.52
CYP3A4 P08684 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
TSHR P16473 2/20 0.46
PIK3CA P42336 1/20 0.46
GABRA1 P14867 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
ALDH1A1 P00352 5/20 0.40
ATP4A P20648 1/20 0.39
ATP4B P51164 1/20 0.39
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPGD P15428 2/20 0.36
CYP2A6 P11509 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31606366 1.00 CD44 (0.52) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL357603 0.85 GABRA1 (0.48) CD44TSHRGABRA1GABRG2GABRB3
SCHEMBL28179325 0.85 TSHR (0.43) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL7760775 0.85 CD44 (0.46) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL3667054 0.83 CD44 (0.54) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL10581584 0.83 CD44 (0.45) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL10581285 0.81 CD44 (0.43) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL30417664 0.81 CD44 (0.52) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL6344760 0.81 CD44 (0.52) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL455161 0.81 CD44 (0.52) CD44CYP3A4TDP1TSHRPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6620823-B2 Antiinflammatory agents; rheumatic disorders BRISTOL-MYERS SQUIBB PHARME COMPANY 2003-09-16 US claimed
US-12486258-B2 Compounds and methods for regulating insulin secretion THE BROAD INSTITUTE, INC. (US) 2025-12-02 US disclosed
EP-4393937-A1 STEROID COMPOUND AND CONJUGATE THEREOF Duality Biologics (Suzhou) Co., Ltd. (CN) 2024-07-03 EP disclosed
CN-114031507-B Synthesis method of o-aminobenzyl alcohol compound 辽宁科信生物科技有限公司 2024-03-22 CN disclosed
CN-110536885-B Process for producing difluoromethylene compound 佐藤制药株式会社 2024-03-08 CN disclosed
CN-115057807-B 3- (2-isocyanobenzyl) indole derivative quorum sensing inhibitor and preparation method and application thereof 海南大学 2023-06-23 CN disclosed
CN-115073473-B Seven-membered ring indoloazepine CYP1B1 enzyme inhibitor, and preparation method and application thereof 海南大学 2023-06-23 CN disclosed
US-20230142508-A1 COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION THE BROAD INSTITUTE, INC. (US) 2023-05-11 US disclosed
US-11555031-B2 Compounds and methods for regulating insulin secretion THE BROAD INSTITUTE, INC. (US) 2023-01-17 US disclosed
US-11495755-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-08 US disclosed
WO-1997027193-A1 IMIDAZOPYRIDINE HALIDES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1997-07-31 WO disclosed
WO-1996040650-A1 CYCLIC AMINE DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONES AS GLUTAMATE RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1996-12-19 WO disclosed
WO-1996040651-A1 ALKYL AMINE DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONES AS GLUTAMATE RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1996-12-19 WO disclosed
EP-0723544-A1 ALKOXY ALKYL CARBAMATES FROM IMIDAZO (1,2-a)PYRIDINES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1996-07-31 EP disclosed
WO-1995010518-A1 ALKOXY ALKYL CARBAMATES FROM IMIDAZO (1,2-a)PYRIDINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1995-04-20 WO disclosed
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP disclosed
US-4920129-A Anti-ulcerative imidazopyridine compounds FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-04-24 US disclosed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
EP-0308917-A2 Imidazopyridine compound, a process for preparation thereof and pharmaceutical compositions comprising them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-03-29 EP disclosed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142508-A1 COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION IAPP, GPR119, PNLIP CD44 2738/4885CYP3A4 4626/4885TDP1 4637/4885
US-11555031-B2 Compounds and methods for regulating insulin secretion IAPP, GPR119, INSR CD44 3841/4885CYP3A4 2639/4885TDP1 4702/4885
US-12486258-B2 Compounds and methods for regulating insulin secretion IAPP, GPR119, PNLIP CD44 2738/4885CYP3A4 4626/4885TDP1 4637/4885
US-11495755-B2 Organic electroluminescent materials and devices RUVBL2, TERT, OR10J3 CD44 3664/4885CYP3A4 2000/4885TDP1 1611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.