Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP3 | P08254 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 3/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348066 | 0.81 | TDP1 (0.55) | MMP1MMP2MMP3MMP9GPR88 | |
| SCHEMBL6344218 | 0.80 | MMP1 (0.49) | MMP1MMP2MMP3MMP9GPR88 | |
| SCHEMBL6354021 | 0.76 | PLA2G1B (0.59) | MMP1MMP2MMP3MMP9GPR88 | |
| SCHEMBL6344869 | 0.76 | MMP2 (0.54) | MMP1MMP2MMP3MMP9MMP7 | |
| SCHEMBL6346137 | 0.74 | FNTA (0.51) | MMP1MMP2MMP3MMP9GPR88 | |
| SCHEMBL6344213 | 0.73 | HPGD (0.55) | MMP1MMP2MMP3MMP9GPR88 | |
| SCHEMBL6343091 | 0.71 | ITGB1 (0.58) | MMP1MMP2MMP3MMP9 | |
| SCHEMBL7824324 | 0.70 | KMT2A (0.63) | GPR88HPGDALDH1A1THRBNPSR1 | |
| SCHEMBL8452846 | 0.67 | POLB (0.43) | GPR88HPGDALDH1A1THRBNPSR1 | |
| SCHEMBL28275970 | 0.67 | GPR88 (0.48) | GPR88HPGDALDH1A1THRBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949534-B2 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. (US) | 2005-09-27 | — | — | US | claimed |
| US-20040053907-A1 | Cell adhesion inhibitors | BIOGEN, INC. A MASSACHUSETTS CORPORATION. | 2004-03-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053907-A1 | Cell adhesion inhibitors | ICAM1, VCAM1, EPCAM | MMP1 192/4885MMP2 621/4885MMP3 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.