Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | ME2 | P23368 | 1/20 | 0.45 |
| ▸ | ME1 | P48163 | 1/20 | 0.45 |
| ▸ | ME3 | Q16798 | 1/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6339829 | 0.90 | ESR1 (0.53) | SENP1CYP1A2HDAC4HDAC2HDAC8 | |
| SCHEMBL6337913 | 0.88 | SENP1 (0.52) | SENP1CYP1A2HDAC4HDAC2HDAC8 | |
| SCHEMBL6342242 | 0.84 | SENP1 (0.47) | SENP1CYP2A6HDAC4HDAC2HDAC8 | |
| SCHEMBL6348777 | 0.84 | SENP1 (0.47) | SENP1CYP2A6HDAC4HDAC2HDAC8 | |
| SCHEMBL6340096 | 0.81 | ME2 (0.73) | SENP1CYP1A2CYP2A6HDAC4HDAC2 | |
| SCHEMBL6349671 | 0.79 | MAPT (0.49) | SENP1HDAC4HDAC2HDAC8ME2 | |
| SCHEMBL6340147 | 0.78 | HSD17B1 (0.47) | SENP1CYP1A2CYP2A6HDAC4HDAC2 | |
| SCHEMBL6348854 | 0.78 | PGR (0.49) | CYP1A2HDAC4HDAC2HDAC8HSD17B1 | |
| SCHEMBL6348816 | 0.77 | HDAC4 (0.49) | SENP1CYP1A2HDAC4HDAC2HDAC8 | |
| SCHEMBL6338544 | 0.76 | SENP1 (0.46) | SENP1CYP2A6ME2ME1ME3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1274655-C | Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same | SERVIER LAB (FR) | 2006-09-13 | — | — | CN | disclosed |
| CN-1628088-A | Novel 3-aryl-2, 5-dihydroxy-1, 4-benzoquinones, process for preparing same and pharmaceutical compositions containing same | SERVIER LAB (FR) | 2005-06-15 | — | — | CN | disclosed |
| US-20050085644-A1 | Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2005-04-21 | — | — | US | disclosed |
| EP-1472208-A1 | NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003066561-A1 | NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085644-A1 | Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same | GPR119, UGT1A1, UGT1A3 | SENP1 4515/4885CYP1A2 61/4885CYP2A6 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.