SCHEMBL6345737

SCHEMBL6345737

Oc1cc2cc(Br)ccc2c(O)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.46
ALOX15 P16050 2/20 0.43
MAPT P10636 4/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CYP2A6 P11509 2/20 0.38
CES2 O00748 1/20 0.38
GALR3 O60755 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
CASP1 P29466 1/20 0.38
CYP2C19 P33261 1/20 0.38
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
BCL2 P10415 1/20 0.35
MCL1 Q07820 1/20 0.35
PIM1 P11309 1/20 0.35
PLAU P00749 1/20 0.35
CTRC Q99895 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6356696 0.78 ERN1 (0.59) ERN1ALOX15MAPTMEN1KMT2A
SCHEMBL22391535 0.78 ERN1 (0.46) ERN1ALOX15MAPTMEN1KMT2A
SCHEMBL9616234 0.75 CYP2A6 (0.50) ERN1MEN1KMT2ACYP2A6CYP1A2
SCHEMBL5743632 0.74 ERN1 (0.50) ERN1ALOX15MAPTMEN1KMT2A
SCHEMBL6348188 0.74 HSD17B10 (0.43) ERN1ALOX15MAPTMEN1KMT2A
SCHEMBL28982382 0.74 ERN1 (0.50) ERN1ALOX15MAPTMEN1KMT2A
SCHEMBL6355043 0.74 TRPA1 (0.44) ALOX15MAPTMEN1KMT2ACYP2A6
SCHEMBL6346791 0.74 CA3 (0.48) ALOX15MAPTMEN1KMT2ACYP2A6
SCHEMBL8934570 0.74 ALOX15 (0.46) ERN1ALOX15MAPTMEN1KMT2A
SCHEMBL30906876 0.74 ALOX15 (0.46) ERN1ALOX15MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878659-B2 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2005-04-12 US disclosed
US-20040072681-A1 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2004-04-15 US disclosed