Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 4/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27839561 | 1.00 | RIPK1 (0.45) | RIPK1KDM4EGAAALDH1A1MEN1 | |
| SCHEMBL24672521 | 0.82 | SIGMAR1 (0.43) | RIPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6092369 | 0.81 | KDM4E (0.58) | RIPK1KDM4EALDH1A1MEN1HPGD | |
| SCHEMBL28857176 | 0.81 | GAA (0.46) | RIPK1KDM4EGAAALDH1A1MEN1 | |
| SCHEMBL28945745 | 0.81 | KDM4E (0.58) | RIPK1KDM4EALDH1A1MEN1HPGD | |
| SCHEMBL30007971 | 0.81 | ROCK2 (0.47) | RIPK1KDM4EGAAALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL12480511 | 0.80 | KDM4E (0.56) | RIPK1KDM4EALDH1A1MEN1HPGD | |
| SCHEMBL10775133 | 0.80 | KDM4E (0.56) | RIPK1KDM4EALDH1A1MEN1HPGD | |
| SCHEMBL10775129 | 0.80 | KDM4E (0.56) | RIPK1KDM4EALDH1A1MEN1HPGD | |
| SCHEMBL633700 | 0.79 | LMNA (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102686565-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (CH) | 2015-09-30 | — | — | CN | disclosed |
| CN-102741242-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2015-07-01 | — | — | CN | disclosed |
| CN-102459250-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2015-05-06 | — | — | CN | disclosed |
| CN-104447707-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2015-03-25 | — | — | CN | disclosed |
| CN-101558059-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-12-03 | — | — | CN | disclosed |
| CN-101528232-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-11-12 | — | — | CN | disclosed |
| CN-103153986-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-11-05 | — | — | CN | disclosed |
| CN-102378762-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2014-10-29 | — | — | CN | disclosed |
| CN-102227407-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2014-10-22 | — | — | CN | disclosed |
| CN-102143959-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2014-10-22 | — | — | CN | disclosed |
| CN-102378762-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-03-14 | — | — | CN | disclosed |
| EP-2419433-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-02-22 | — | — | EP | disclosed |
| CN-102227407-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-10-26 | — | — | CN | disclosed |
| CN-102143959-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-08-03 | — | — | CN | disclosed |
| CN-102015692-A | Heterocyclic derivatives as hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-04-13 | — | — | CN | disclosed |
| CN-102007122-A | Imidazolyl biphenyl imidazoles as hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-04-06 | — | — | CN | disclosed |
| CN-101998952-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-03-30 | — | — | CN | disclosed |
| WO-2010120621-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-21 | — | — | WO | disclosed |
| CN-101754966-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2010-06-23 | — | — | CN | disclosed |
| CN-101558059-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | CN | disclosed |