Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485995 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL6047705 | 0.85 | SMPD1 (0.42) | SMPD1LAP3METAP1MMP1MMP2 | |
| SCHEMBL27505457 | 0.85 | SMPD1 (0.42) | SMPD1LAP3METAP1MMP1MMP2 | |
| SCHEMBL497286 | 0.73 | LAP3 (0.39) | SMPD1LAP3METAP1MMP1MMP2 | |
| SCHEMBL6980344 | 0.73 | — | — | |
| SCHEMBL19245350 | 0.72 | TRPM8 (0.35) | SMPD1LAP3METAP1MMP1MMP2 | |
| SCHEMBL16225024 | 0.72 | SMPD1 (0.42) | SMPD1LAP3METAP1MMP1MMP2 | |
| SCHEMBL2185946 | 0.72 | LAP3 (0.37) | SMPD1LAP3METAP1MMP1MMP2 | |
| SCHEMBL9259903 | 0.72 | — | — | |
| SCHEMBL777741 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838565-B2 | Substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-01-04 | — | — | US | disclosed |
| US-20040138309-A1 | Novel substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM (DE) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138309-A1 | Novel substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | F11, F12, SERPINC1 | SMPD1 2033/4885LAP3 1891/4885METAP1 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.