Sugi Predict

Sugi Predict / Compounds / SCHEMBL6347376

SCHEMBL6347376

SCHEMBL6347376

CCOC(=O)[C@H]1[C@H](NC(=O)OCc2ccccc2)CCN1C(=O)OC(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CPB1 P15086 2/20 0.46
▸ CTSL P07711 2/20 0.46
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ KLK7 P49862 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ SYK P43405 1/20 0.41
▸ CTSB P07858 1/20 0.41
▸ CTSK P43235 1/20 0.41
▸ FKBP1A P62942 3/20 0.41
▸ ABCB1 P08183 1/20 0.41
▸ TSHR P16473 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ PDE4B Q07343 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18335958 1.00 CPB1 (0.46) CPB1CTSLMEN1KMT2AKLK7
SCHEMBL18337377 0.93 CPB1 (0.48) CPB1CTSLKLK7ALDH1A1GAA
SCHEMBL4037641 0.92 CPB1 (0.45) CPB1CTSLMEN1KMT2AKLK7
SCHEMBL5941298 0.92 CPB1 (0.45) CPB1CTSLMEN1KMT2AKLK7
SCHEMBL25907340 0.92 CPB1 (0.53) CPB1CTSLKLK7ALDH1A1GAA
SCHEMBL32672364 0.92 CPB1 (0.53) CPB1CTSLKLK7ALDH1A1GAA
SCHEMBL5941341 0.90 ALDH1A1 (0.47) CPB1CTSLKLK7ALDH1A1GAA
SCHEMBL14468657 0.90 ALDH1A1 (0.47) CPB1CTSLKLK7ALDH1A1GAA
SCHEMBL4040280 0.90 ALDH1A1 (0.47) CPB1CTSLKLK7ALDH1A1GAA
SCHEMBL31058400 0.90 ALDH1A1 (0.47) CPB1CTSLKLK7ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8772450-B2 Beta-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2014-07-08 — — US disclosed
US-8772450-B2 Beta-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2014-07-08 — — US disclosed
US-20130023644-A1 BETA-AMINO ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION 2013-01-24 — — US disclosed
US-20130023644-A1 BETA-AMINO ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION 2013-01-24 — — US disclosed
US-20070154882-A1 Beta-polypeptides that inhibit cytomegalovirus infection NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-07-05 — — US disclosed
US-20070123709-A1 Beta-amino acids NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-05-31 — — US disclosed
US-6949546-B2 N-ureidoheterocycloalkyl-piperidines as modulators of chemokine receptor activity BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2005-09-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070123709-A1 Beta-amino acids BCAT1, MARCKS, YWHAZ CPB1 225/4885CTSL 124/4885MEN1 1614/4885
US-20130023644-A1 BETA-AMINO ACIDS BCAT1, MARCKS, YWHAZ CPB1 225/4885CTSL 124/4885MEN1 1614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.