Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5941341 | 1.00 | ALDH1A1 (0.47) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL4040280 | 1.00 | ALDH1A1 (0.47) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL31058400 | 1.00 | ALDH1A1 (0.47) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL18337377 | 0.93 | CPB1 (0.48) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL32672364 | 0.92 | CPB1 (0.53) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL25907340 | 0.92 | CPB1 (0.53) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL6347376 | 0.90 | CPB1 (0.46) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL18335958 | 0.90 | CPB1 (0.46) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL18337016 | 0.89 | CPB1 (0.45) | ALDH1A1GAACPB1CTSLTSHR | |
| SCHEMBL18337160 | 0.89 | CPB1 (0.45) | ALDH1A1GAACPB1CTSLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3683222-B1 | NOVEL BICYCLIC OR TRICYCLIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2021-10-06 | — | — | EP | disclosed |
| EP-3683222-A1 | NOVEL BICYCLIC OR TRICYCLIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2020-07-22 | — | — | EP | disclosed |
| US-10065972-B2 | Bicyclic or tricyclic heterocyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2018-09-04 | — | — | US | disclosed |
| EP-3135674-A1 | NOVEL BICYCLIC OR TRICYCLIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-20160376289-A1 | NOVEL BICYCLIC OR TRICYCLIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2016-12-29 | — | — | US | disclosed |
| US-8772450-B2 | Beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130023644-A1 | BETA-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-01-24 | — | — | US | disclosed |
| US-20070154882-A1 | Beta-polypeptides that inhibit cytomegalovirus infection | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-07-05 | — | — | US | disclosed |
| US-20070123709-A1 | Beta-amino acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123709-A1 | Beta-amino acids | BCAT1, MARCKS, YWHAZ | ALDH1A1 4837/4885GAA 3215/4885CPB1 225/4885 |
| US-20160376289-A1 | NOVEL BICYCLIC OR TRICYCLIC HETEROCYCLIC COMPOUND | CBR3, CBR1, CYCS | ALDH1A1 2826/4885GAA 4633/4885CPB1 2213/4885 |
| US-20130023644-A1 | BETA-AMINO ACIDS | BCAT1, MARCKS, YWHAZ | ALDH1A1 4837/4885GAA 3215/4885CPB1 225/4885 |
| US-10065972-B2 | Bicyclic or tricyclic heterocyclic compound | CBR3, CBR1, CYCS | ALDH1A1 3047/4885GAA 4645/4885CPB1 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.