Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14415589 | 0.89 | IDO1 (0.46) | SLC6A2SLC6A3CNR2IDO1TDO2 | |
| SCHEMBL6001243 | 0.89 | IDO1 (0.46) | SLC6A2SLC6A3CNR2IDO1TDO2 | |
| SCHEMBL14415587 | 0.89 | IDO1 (0.46) | SLC6A2SLC6A3CNR2IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL4559164 | 0.82 | IDO1 (0.50) | SLC6A2SLC6A3ADRB2IDO1TDO2 | |
| SCHEMBL14415581 | 0.79 | PNMT (0.55) | SLC6A2SLC6A3ADRB2PNMTAOC3 | |
| SCHEMBL14415580 | 0.79 | PNMT (0.55) | SLC6A2SLC6A3ADRB2PNMTAOC3 | |
| SCHEMBL14415582 | 0.79 | PNMT (0.55) | SLC6A2SLC6A3ADRB2PNMTAOC3 | |
| SCHEMBL17519152 | 0.76 | OPRL1 (0.43) | ADRB2IDO1TDO2AOC3OPRL1 | |
| Hydrochloric Acid SCHEMBL11404032 | 0.76 | ALDH1A1 (0.42) | SLC6A2SLC6A3OPRK1SLC6A4 | |
| Hydrochloric Acid SCHEMBL11404035 | 0.76 | ALDH1A1 (0.42) | SLC6A2SLC6A3OPRK1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014788-A1 | Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5) | ASTRAZENECA AB (SE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014788-A1 | Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5) | CCR5, CCR2, CCL2 | SLC6A2 1806/4885SLC6A3 1927/4885ADRB2 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.