Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.79 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.64 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.64 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.64 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.57 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.53 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307201 | 0.88 | KCNK2 (0.64) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL21931016 | 0.88 | ACLY (1.00) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL1307097 | 0.87 | AKR1C2 (0.76) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL17166275 | 0.86 | AKR1C2 (0.73) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6833304 | 0.86 | AKR1C2 (0.61) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6349749 | 0.85 | ACLY (0.58) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL7040635 | 0.85 | ACLY (0.61) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL9513479 | 0.83 | MAPT (0.80) | AKR1C2AKR1C1AKR1C4AKR1C3KCNK2 | |
| SCHEMBL1308635 | 0.83 | AKR1C2 (0.65) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6348852 | 0.82 | AKR1C2 (0.72) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | ACLY 1720/4885AKR1C2 3012/4885AKR1C1 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.