Flurofamide

Flurofamide

SCHEMBL635029

NP(N)(=O)NC(=O)c1ccc(F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAOA P21397 1/20 0.49
PTPN1 P18031 1/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
HDAC1 Q13547 1/20 0.47
MITF O75030 1/20 0.47
NPC1 O15118 3/20 0.46
CYP2D6 P10635 1/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10936559 0.89 MPO (0.44) MEN1KMT2AHDAC1CYP2D6CA1
SCHEMBL11435601 0.81 LMNA (0.55) MEN1KMT2AHDAC1NPC1RAB9A
SCHEMBL8656271 0.80 CES2 (0.55) PTPN1CES2CES1NPC1RAB9A
SCHEMBL8656312 0.79 ALDH1A1 (0.59) MEN1KMT2ACES2CES1HDAC1
SCHEMBL1504927 0.79 KDM4E (0.61) MEN1KMT2AMAOACES2CES1
SCHEMBL8654622 0.79 CES2 (0.48) CES2CES1HDAC1NPC1RAB9A
SCHEMBL11435184 0.79 MEN1 (0.50) MEN1KMT2AMAOAPTPN1CES2
SCHEMBL1504747 0.78 HDAC3 (0.54) MEN1KMT2APTPN1CES1HDAC1
SCHEMBL8654897 0.77 HDAC1 (0.62) MEN1KMT2ACES2CES1HDAC1
SCHEMBL10493828 0.77 ALDH1A1 (0.45) MEN1KMT2AMAOAPTPN1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
EP-2859039-A2 ODOUR-CONTROL SUPERABSORBENT BASF SE (DE) 2015-04-15 EP claimed
EP-2701527-A2 PRODUCTION OF CHESSE WITH S. THERMOPHILUS Dupont Nutrition Biosciences ApS (DK) 2014-03-05 EP claimed
WO-2013182469-A2 ODOUR-CONTROL SUPERABSORBENT BASF SE (DE) 2013-12-12 WO claimed
US-20120288586-A1 PRODUCTION OF CHEESE WITH S. THERMOPHILUS DUPONT NUTRITION BIOSCIENCES APS (DK) 2012-11-15 US claimed
WO-2012145629-A2 PRODUCTION OF CHEESE WITH S. THERMOPHILUS DANISCO A/S (DK) 2012-10-26 WO claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-4182881-A N-[Diaminophosphinyl]arylcarboxamides MORTON-NORWICH PRODUCTS, INC. (US) 1980-01-08 US claimed
WO-2026098996-A1 ODOR-CONTROL SUPERABSORBENT COMPRISING ACTIVATED CARBON MATERIAL HAVING A TRIMODAL PORE RADIUS DISTRIBUTION BASF SE (DE) 2026-05-15 WO disclosed
US-12569483-B2 Methods for objective assessment of memory, early detection of risk for Alzheimer's disease, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2026-03-10 US disclosed
US-4289907-A Process for preparing N-alkyl-nitroanilines UNION CARBIDE CORPORATION (US) 1981-09-15 US disclosed
US-4182881-A N-[Diaminophosphinyl]arylcarboxamides MORTON-NORWICH PRODUCTS, INC. (US) 1980-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569483-B2 Methods for objective assessment of memory, early detection of risk for Alzheimer's disease, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs PSMB3, THRB, GRIN2B MEN1 4579/4885KMT2A 1593/4885MAOA 1920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.