Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 9/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PLG | P00747 | 6/20 | 0.40 |
| ▸ | PLAU | P00749 | 5/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6350375 | 0.99 | ACACB (0.41) | ACACBF10PRSS1F2PLG | |
| SCHEMBL6340740 | 0.90 | F10 (0.39) | ACACBF10PRSS1F2PLG | |
| SCHEMBL7560667 | 0.89 | F10 (0.41) | ACACBF10PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7558907 | 0.88 | F10 (0.41) | ACACBF10PRSS1F2 | |
| Hydrochloric Acid SCHEMBL6342450 | 0.87 | NPC1 (0.41) | ACACBF10PRSS1F2PLG | |
| SCHEMBL6554435 | 0.84 | F10 (0.42) | ACACBF10PRSS1F2PLG | |
| Hydrochloric Acid SCHEMBL6556783 | 0.83 | ITGB3 (0.41) | ACACBF10PRSS1F2PLG | |
| Hydrochloric Acid SCHEMBL7558537 | 0.83 | F10 (0.41) | ACACBF10PRSS1F2PLG | |
| Hydrochloric Acid SCHEMBL6341161 | 0.81 | ACE (0.40) | F10PRSS1F2 | |
| SCHEMBL7558652 | 0.78 | F10 (0.49) | F10PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838565-B2 | Substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-01-04 | — | — | US | claimed |
| US-20040138309-A1 | Novel substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM (DE) | 2004-07-15 | — | — | US | claimed |
| WO-2004013128-A1 | NOVEL SUBSTITUTED BENZAMIDES PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM (DE) | 2004-02-12 | — | — | WO | claimed |
| US-6838565-B2 | Substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-01-04 | — | — | US | disclosed |
| US-6838565-B2 | Substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-01-04 | — | — | US | disclosed |
| US-20040138309-A1 | Novel substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM (DE) | 2004-07-15 | — | — | US | disclosed |
| US-20040138309-A1 | Novel substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM (DE) | 2004-07-15 | — | — | US | disclosed |
| WO-2004013128-A1 | NOVEL SUBSTITUTED BENZAMIDES PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM (DE) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138309-A1 | Novel substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | F11, F12, SERPINC1 | ACACB 558/4885F10 11/4885PRSS1 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.