SCHEMBL7560667

SCHEMBL7560667

Cc1cc(C(=O)NC(CC(=O)O)c2cc(C(=N)N)ccc2O)ccc1C(=O)N1CCCC1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F10 P00742 3/20 0.41
PRSS1 P07477 2/20 0.41
ITGB3 P05106 12/20 0.39
ITGB1 P05556 1/20 0.39
ITGAV P06756 1/20 0.39
ITGA5 P08648 1/20 0.39
ITGB5 P18084 1/20 0.39
ITGB6 P18564 1/20 0.39
ITGB8 P26012 1/20 0.39
ITGA8 P53708 1/20 0.39
F2 P00734 2/20 0.39
ITGA2B P08514 11/20 0.39
CTSA P10619 3/20 0.38
ACACB O00763 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7558907 0.99 F10 (0.41) F10PRSS1ITGB3ITGB1ITGAV
Hydrochloric Acid SCHEMBL6556783 0.89 ITGB3 (0.41) F10PRSS1ITGB3F2ITGA2B
SCHEMBL6350317 0.89 ACACB (0.41) F10PRSS1F2ACACB
Hydrochloric Acid SCHEMBL6350375 0.88 ACACB (0.41) F10PRSS1F2ACACB
SCHEMBL6554435 0.86 F10 (0.42) F10PRSS1ITGB3F2ITGA2B
SCHEMBL7558652 0.85 F10 (0.49) F10PRSS1ITGB3F2ITGA2B
Hydrochloric Acid SCHEMBL7558537 0.85 F10 (0.41) F10PRSS1ITGB3F2ITGA2B
Hydrochloric Acid SCHEMBL6554532 0.85 F10 (0.48) F10PRSS1ITGB3F2ITGA2B
SCHEMBL6555829 0.85 ACACB (0.42) CTSAACACB
SCHEMBL6340740 0.83 F10 (0.39) F10PRSS1F2ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020151534-A1 Antithrombotic compounds BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US claimed
US-20020151534-A1 Antithrombotic compounds BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151534-A1 Antithrombotic compounds SERPINC1, PF4, F2 F10 35/4885PRSS1 776/4885ITGB3 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.