Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987672 | 0.87 | L3MBTL1 (0.65) | CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL11089154 | 0.83 | CYP1A2 (0.66) | CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL3932468 | 0.79 | HTR1A (0.54) | CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL30496731 | 0.79 | HTR1A (0.54) | CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL6077378 | 0.79 | L3MBTL1 (0.57) | CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL11957894 | 0.79 | PRMT5 (0.54) | CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL23521792 | 0.79 | CYP2D6 (0.49) | CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL29807861 | 0.79 | CYP2D6 (0.49) | CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL4573627 | 0.78 | IDO1 (0.52) | CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL8042005 | 0.78 | L3MBTL1 (0.60) | CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | ABBOTT LABORATORIES | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | GPR119, GIPR, GCGR | CYP1A2 3946/4885CYP2D6 3054/4885CYP2C9 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.