SCHEMBL8042005

SCHEMBL8042005

Clc1ccc(CNCc2ccccc2)cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.60
PLA2G1B P04054 1/20 0.59
POLB P06746 1/20 0.59
ATG4B Q9Y4P1 1/20 0.59
SIGMAR1 Q99720 1/20 0.53
TRPV1 Q8NER1 1/20 0.53
SLC6A2 P23975 1/20 0.51
SLC6A4 P31645 1/20 0.51
SLC6A3 Q01959 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
PRMT5 O14744 1/20 0.49
WDR77 Q9BQA1 1/20 0.49
DNM1 Q05193 1/20 0.48
ALDH1A1 P00352 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8987672 0.89 L3MBTL1 (0.65) L3MBTL1PLA2G1BPOLBATG4BSIGMAR1
SCHEMBL7760994 0.86 KDM4E (0.60) L3MBTL1PLA2G1BPOLBATG4BSLC6A4
SCHEMBL6077378 0.86 L3MBTL1 (0.57) L3MBTL1PLA2G1BPOLBATG4BSIGMAR1
SCHEMBL18768843 0.85 CYP1A2 (0.71) PLA2G1BPOLBATG4BSIGMAR1TRPV1
SCHEMBL6076785 0.83 SIGMAR1 (0.63) PLA2G1BPOLBATG4BSIGMAR1TRPV1
SCHEMBL11089154 0.81 CYP1A2 (0.66) L3MBTL1PLA2G1BPOLBATG4BSIGMAR1
SCHEMBL18768854 0.81 CYP1A2 (0.57) L3MBTL1PLA2G1BPOLBATG4BCYP1A2
SCHEMBL10054993 0.80 MEN1 (0.74) SIGMAR1MEN1KMT2ATDP1BCHE
Fluoride SCHEMBL634375 0.80 MEN1 (0.74) SIGMAR1MEN1KMT2ATDP1BCHE
SCHEMBL25612810 0.80 SLC6A2 (0.49) L3MBTL1PLA2G1BPOLBATG4BSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3363288-B1 COMPOSITION FOR DESTRUCTION OF MICROALGAE OR MOSSES CUREARTH INC (KR) 2022-09-07 EP disclosed
CN-108347925-B Compositions for destroying microalgae or moss 株式会社CUREARTH 2021-07-16 CN disclosed
US-11044909-B2 Composition for destruction of microalgae or sphaerocarpus CUREARTH, INC. (KR) 2021-06-29 US disclosed
US-11044909-B2 Composition for destruction of microalgae or sphaerocarpus CUREARTH, INC. (KR) 2021-06-29 US disclosed
US-20180271091-A1 COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS CUREARTH, INC. (KR) 2018-09-27 US disclosed
EP-3363288-A1 COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS Curearth, Inc. (KR) 2018-08-22 EP disclosed
CN-108347925-A composition for destroying microalgae or moss 株式会社CUREARTH 2018-07-31 CN disclosed
WO-2017065401-A1 COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS 주식회사 큐얼스 2017-04-20 WO disclosed
WO-2009071706-A1 PYRAZOLEPYRIMIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES GALAPAGOS NV (BE) 2009-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180271091-A1 COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS TK1, TRHDE, TK2 L3MBTL1 3467/4885PLA2G1B 805/4885POLB 1042/4885
US-11044909-B2 Composition for destruction of microalgae or sphaerocarpus TK1, TRHDE, TK2 L3MBTL1 3467/4885PLA2G1B 805/4885POLB 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.