SCHEMBL635048

SCHEMBL635048

NCC(=O)Oc1ccccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2B Q14289 1/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
PKM P14618 1/20 0.45
CXCL8 P10145 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
LMNA P02545 1/20 0.44
BCHE P06276 1/20 0.44
HDAC6 Q9UBN7 1/20 0.43
HTT P42858 2/20 0.42
HPGD P15428 1/20 0.42
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
TP53 P04637 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
MAPT P10636 3/20 0.42
POLB P06746 3/20 0.41
RAB9A P51151 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30140858 1.00 PTK2B (0.45) PTK2BMEN1KMT2APKMCXCL8
SCHEMBL27985462 0.98 PTK2B (0.44) PTK2BMEN1KMT2APKMCXCL8
Hydrochloric Acid SCHEMBL27850668 0.98 PTK2B (0.44) PTK2BMEN1KMT2APKMCXCL8
SCHEMBL28122214 0.98 PTK2B (0.44) PTK2BMEN1KMT2APKMCXCL8
SCHEMBL5842469 0.85 MRGPRX4 (0.43) MEN1KMT2AHTTTP53L3MBTL1
SCHEMBL8496813 0.84 PTK2B (0.47) PTK2BMEN1KMT2APKMCXCL8
SCHEMBL28189795 0.82 MEN1 (0.50) PTK2BMEN1KMT2APKMCXCL8
SCHEMBL27645038 0.82 KMT2A (0.46) PTK2BMEN1KMT2APKMCXCL8
SCHEMBL8498810 0.81 KMT2A (0.50) PTK2BMEN1KMT2APKMCXCL8
SCHEMBL578720 0.81 ELANE (0.46) PTK2BMEN1KMT2APKMCXCL8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115784914-A Preparation method of o-chlorophenylglycine 石家庄中硕科技有限公司 2023-03-14 CN claimed
CN-218307945-U Synthesis device for preparing o-chlorobenzene glycine intermediate 抚顺顺能化工有限公司 2023-01-17 CN claimed
CN-114853623-A Preparation method of S- (+) -o-chlorophenylglycine methyl ester tartrate 河南优凯制药有限公司 2022-08-05 CN claimed
CN-114685300-A Preparation method of o-chlorophenylglycine 抚顺顺能化工有限公司 2022-07-01 CN claimed
CN-114507650-A Leucine dehydrogenase mutant and application thereof in synthesis of (S) -o-chlorophenylglycine 浙江工业大学 2022-05-17 CN claimed
CN-213866023-U O chlorobenzene glycine decoloration equipment 黑龙江泰纳科技集团股份有限公司 2021-08-03 CN claimed
CN-111440139-A Preparation method of clopidogrel sulfonate impurity 廊坊市泽康医药科技有限公司 2020-07-24 CN claimed
CN-107628955-B Amino inhibitor for water-based drilling fluid, water-based drilling fluid system and preparation method 中国石油集团长城钻探工程有限公司钻井液公司 2020-06-02 CN claimed
CN-210495690-U A dust collecting equipment for producing o-chlorobenzene glycine 石家庄中硕科技有限公司 2020-05-12 CN claimed
CN-210496365-U Preparation facilities of o chlorobenzene glycine 石家庄中硕科技有限公司 2020-05-12 CN claimed
CN-101560533-A Preparation method of S-(+)-o-chlorobenzoyl glycine SUZHOU LIXIN PHARMACEUTICAL CO (CN) 2009-10-21 CN claimed
CN-100548969-C A kind of preparation method of o-chlorobenzene glycine ZHEJIANG PULUO MEDICINE TECHNO (CN) 2009-10-14 CN claimed
EP-2078025-A2 PROCESS FOR THE SYNTHESIS OF CLOPIDOGREL AND NEW FORMS OF PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF KRKA, tovarna zdravil, d.d., Novo mesto (SI) 2009-07-15 EP claimed
CN-101368199-A Method for preparing D-aminophenol with immobilization penicillin acylated enzyme catalysis UNIV CHONGQING POSTS & TELECOM (CN) 2009-02-18 CN claimed
WO-2008034912-A2 PROCESS FOR THE SYNTHESIS OF CLOPIDOGREL AND NEW FORMS OF PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) 2008-03-27 WO claimed
CN-101092379-A Method for synthesizing optically active laevogyrate and dexiotropous camphor sulfonic acid KANGFUSAIER MEDICINES TECH CO (CN) 2007-12-26 CN claimed
CN-101058547-A Method of preparing o-chlorophenyl glycine ZHEJIANG PULUO MEDICINE TECHNO (CN) 2007-10-24 CN claimed
WO-2007094006-A1 PROCESS FOR PREPARATION OF CLOPIDOGREL BISULFATE FORM 1 LEE PHARMA LIMITED (IN) 2007-08-23 WO claimed
US-20070191609-A1 PROCESS FOR PREPARATION OF CLOPIDOGREL BISULPHATE FORM-1 LEE PHARMA LIMITED (IN) 2007-08-16 US claimed
CN-101003822-A Method for producing D amino acid by immobilizing acylation enzyme of penicillin CHENGDU ORGANIC CHEMISTRY C A (CN) 2007-07-25 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191609-A1 PROCESS FOR PREPARATION OF CLOPIDOGREL BISULPHATE FORM-1 SULT1A1, SF1, ADH1C PTK2B 646/4885MEN1 2059/4885KMT2A 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.