Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.55 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6346632 | 0.92 | SIRT2 (0.56) | SIRT2MCL1BCL2A1LTC4SKMT2A | |
| Hydrochloric Acid SCHEMBL6350733 | 0.91 | SIRT2 (0.55) | SIRT2MCL1BCL2A1LTC4SKMT2A | |
| SCHEMBL6350712 | 0.84 | AKR1C2 (0.63) | MCL1BCL2A1LTC4SKMT2AMEN1 | |
| SCHEMBL6353963 | 0.82 | KMT2A (0.62) | MCL1BCL2A1LTC4SKMT2AMEN1 | |
| SCHEMBL6349884 | 0.81 | SMPD1 (0.61) | KMT2AMEN1ALDH1A1MAOBAKR1C2 | |
| SCHEMBL6818090 | 0.81 | ALB (0.65) | MCL1BCL2A1LTC4SKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6833139 | 0.80 | ALB (0.64) | MCL1BCL2A1LTC4SKMT2AMEN1 | |
| SCHEMBL6359203 | 0.80 | KMT2A (0.58) | LTC4SKMT2AMEN1PKMALDH1A1 | |
| SCHEMBL6351469 | 0.80 | AKR1C2 (0.66) | LTC4SKMT2AMEN1PKMALDH1A1 | |
| SCHEMBL6352168 | 0.80 | KMT2A (0.47) | SIRT2MCL1BCL2A1LTC4SKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | SIRT2 3380/4885MCL1 2360/4885BCL2A1 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.