Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678335 | 0.86 | MAPT (0.46) | MAPT | |
| SCHEMBL6348734 | 0.82 | AKR1C4 (0.58) | ALDH1A1LMNAMAPT | |
| SCHEMBL678714 | 0.82 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL678531 | 0.81 | HTT (0.64) | HTT | |
| SCHEMBL6350942 | 0.79 | GFER (0.70) | ALDH1A1MAPTHTT | |
| SCHEMBL4587994 | 0.78 | MAPT (0.52) | ALDH1A1LMNAMAPTHTT | |
| SCHEMBL6353963 | 0.78 | KMT2A (0.62) | ALDH1A1MAPTHTT | |
| SCHEMBL679409 | 0.77 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL677700 | 0.77 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL678402 | 0.76 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | ALDH1A1 462/4885LMNA 4552/4885MAPT 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.