Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | P4HB | P07237 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353196 | 0.93 | ALB (0.53) | SMN1; SMN2LMNAALDH1A1ALBALOX15 | |
| SCHEMBL6359345 | 0.93 | ALB (0.53) | SMN1; SMN2LMNAALDH1A1ALBALOX15 | |
| SCHEMBL6352948 | 0.90 | APEX1 (0.63) | SMN1; SMN2LMNAALDH1A1ALBMEN1 | |
| SCHEMBL6359077 | 0.84 | ALB (0.56) | SMN1; SMN2LMNAALDH1A1ALBALOX15 | |
| SCHEMBL6353472 | 0.83 | APEX1 (0.56) | SMN1; SMN2LMNAALDH1A1ALBMEN1 | |
| SCHEMBL6357082 | 0.83 | APEX1 (0.56) | SMN1; SMN2LMNAALDH1A1ALBMEN1 | |
| SCHEMBL6353693 | 0.82 | ALB (0.55) | SMN1; SMN2LMNAALDH1A1ALBHTT | |
| SCHEMBL6821593 | 0.81 | LMNA (0.39) | SMN1; SMN2LMNAALDH1A1ALBMEN1 | |
| SCHEMBL6352320 | 0.80 | TAS2R14 (0.57) | SMN1; SMN2LMNAALDH1A1ALBMEN1 | |
| SCHEMBL6352988 | 0.80 | TAS2R14 (0.56) | SMN1; SMN2LMNAALDH1A1ALBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | SMN1; SMN2 3015/4885LMNA 4552/4885ALDH1A1 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.