SCHEMBL6354094

SCHEMBL6354094

Cc1ccc(S(=O)(=O)NCCBr)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.66
MEN1 O00255 1/20 0.66
KMT2A Q03164 1/20 0.66
CA12 O43570 2/20 0.60
CA9 Q16790 2/20 0.60
CA2 P00918 1/20 0.60
LMNA P02545 1/20 0.58
HPGD P15428 1/20 0.58
HTT P42858 1/20 0.58
ALOX15 P16050 1/20 0.58
GAA P10253 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.54
GBA1 P04062 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
ATM Q13315 1/20 0.54
MBTD1 Q05BQ5 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.53
CYP19A1 P11511 1/20 0.53
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7092060 0.89 ALDH1A1 (0.70) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL5567042 0.88 ALDH1A1 (0.75) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL7094581 0.87 ALDH1A1 (0.68) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL8213969 0.86 ALDH1A1 (0.72) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL4581466 0.85 ALDH1A1 (0.71) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL6355304 0.85 ALDH1A1 (0.71) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL10176542 0.84 ALDH1A1 (0.68) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL7201051 0.84 ALDH1A1 (0.86) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL7094852 0.84 ALDH1A1 (0.79) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL18377408 0.82 SIGMAR1 (0.67) ALDH1A1MEN1KMT2ACA2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010940-A Citric acid-based fluorescent dye with long-life characteristic of water, and preparation method and application thereof 西湖大学 2026-05-12 CN claimed
CN-122010940-A Citric acid-based fluorescent dye with long-life characteristic of water, and preparation method and application thereof 西湖大学 2026-05-12 CN disclosed
CN-110191878-B Bicyclo [1.1.1] pentane inhibitors of dual leucine zipper (DLK) kinases for the treatment of diseases 德州大学系统董事会 2023-05-26 CN disclosed
CN-110669088-B N- (2-ethylamine) benzenesulfonylamino cordycepin derivative and preparation method and application thereof 成都阿奇生物医药科技有限公司 2023-03-28 CN disclosed
CN-110669088-A N- (2-ethylamine) benzenesulfonylamino cordycepin derivative and preparation method and application thereof 成都阿奇生物医药科技有限公司 2020-01-10 CN disclosed
WO-2019025153-A1 USE OF SUBSTITUTED N-SULFONYL-N'-ARYL DIAMINOALKANES AND N-SULFONYL-N'-HETEROARYL DIAMINOALKANES OR SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-07 WO disclosed
US-20050182069-A1 Enantiomers of 1-[(4-chlorophenyl) phenylmethyl]-4-[(4-methylphenyl) sulfonyl] piperazine COSSEMENT ERIC (BE) 2005-08-18 US disclosed
US-20050176732-A1 Enantiomers of 1-(4-chlorophenyl)phenylmethyl]-4-[(4-methylphenyl)sulfonyl]piperazine COSSEMENT ERIC (BE) 2005-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050176732-A1 Enantiomers of 1-(4-chlorophenyl)phenylmethyl]-4-[(4-methylphenyl)sulfonyl]piperazine QDPR, PRLHR, OPRK1 ALDH1A1 340/4885MEN1 3989/4885KMT2A 1901/4885
US-20050182069-A1 Enantiomers of 1-[(4-chlorophenyl) phenylmethyl]-4-[(4-methylphenyl) sulfonyl] piperazine QDPR, COMT, PRLHR ALDH1A1 294/4885MEN1 3555/4885KMT2A 2318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.