Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30613082 | 0.84 | NPC1 (0.57) | NPC1KMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL10603799 | 0.84 | NPC1 (0.57) | NPC1KMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL4261842 | 0.82 | MAPK1 (0.56) | NPC1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL28007482 | 0.82 | CA1 (0.51) | NPC1KMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL8689243 | 0.81 | TDP1 (0.68) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL16650906 | 0.77 | ALDH1A1 (0.60) | KMT2AMEN1L3MBTL1HPGDALDH1A1 | |
| SCHEMBL31236186 | 0.77 | ALDH1A1 (0.62) | NPC1KMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL9835752 | 0.77 | NPC1 (0.53) | NPC1KMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL30499697 | 0.77 | KIF11 (0.51) | NPC1KMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL5360905 | 0.77 | L3MBTL1 (0.58) | NPC1KMT2AMEN1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6888003-B2 | Method for producing 7-(pyrazole-3-yl) benzoxazoles | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-03 | — | — | US | disclosed |
| EP-1272486-B1 | METHOD FOR PRODUCING 7-(PYRAZOLE-3-YL) BENZOXAZOLES | BASF AG (DE) | 2004-08-11 | — | — | EP | disclosed |
| US-20030050477-A1 | Method for producing 7-(pyrazole-3-yl) benzoxazoles | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-13 | — | — | US | disclosed |
| EP-1272486-A1 | METHOD FOR PRODUCING 7-(PYRAZOLE-3-YL) BENZOXAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001068644-A1 | METHOD FOR PRODUCING 7-(PYRAZOLE-3-YL) BENZOXAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-20 | — | — | WO | disclosed |
| EP-0318649-B1 | Positive-working radiation-sensitive composistion and radiation-sensitive recording material produced therefrom for high-energy radiation | HOECHST AG (DE) | 1996-01-03 | — | — | EP | disclosed |
| US-5403697-A | Comprising compound which forms acid after high energy radiation and an acid-cleavable compound, polymeric binder | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-04 | — | — | US | disclosed |
| EP-0318649-A2 | Positive-working radiation-sensitive composistion and radiation-sensitive recording material produced therefrom for high-energy radiation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-06-07 | — | — | EP | disclosed |
| US-4575479-A | HIGH SPEED; PHOTO-FIXING ABILITY | RICOH COMPANY, LTD. (JP) | 1986-03-11 | — | — | US | disclosed |
| US-4542394-A | MULTILAYER-DIAZONIUM LAYER AND COUPLER LAYER CONTAINING BENZIMIDAZOLE COMPOUND | RICOH COMPANY, LTD. (JP) | 1985-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050477-A1 | Method for producing 7-(pyrazole-3-yl) benzoxazoles | F7, F9, TPO | NPC1 3671/4885KMT2A 2545/4885MEN1 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.